Neuroendocrine Control of Puberty

  • Carine Villanueva
  • Nicolas de RouxEmail author


Puberty results from the complete maturation of the GnRH neuronal network. It marks the reactivation of this network after a long period of quiescence during childhood. This reactivation causes an increase of sexual hormones leading to the appearance of secondary sexual characteristic. Several neuropeptides have now been described. The age at puberty is a sensitive indicator of evolution.


Median Eminence Arcuate Nucleus GnRH Neuron Hypogonadotropic Hypogonadism Central Precocious Puberty 
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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.INSERM U1141, Université Paris DiderotParisFrance
  2. 2.Laboratoire de Biochimie-HormonologieHôpital Robert DebréParisFrance

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