A stenosis in the upper urinary tract (UUT) can be of non-malignant or malignant origin.
In stenosis in the UUT, factors of significance for the choice of the treatment modality and for its results are location and length of the stricture, and renal function. Also the origin of the stricture, malignant or non-malignant, should be taken into consideration. Therefore, these factors should be adequately investigated prior to treatment.
Symptoms and/or findings suspicious for transitional cell carcinoma (TCC) in the UUT are strong indications for endoscopic examination. In case of TCC, for patients with solitary kidney or poor renal function the choice of endoscopic organ-sparing treatment or of radical nephroureterectomy will have important impact on the quality of life.
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