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Apelin Metabolic Functions

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Physiology and Physiopathology of Adipose Tissue

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Abstract

Adipose tissue modulates metabolism by secreting a variety factors with altered production during obesity. Apelin, a small peptide, known as the ligand of the G protein-coupled receptor APJ is present in different tissues and also produced and secreted by adipocytes. Apelin has emerged as a new player in both glucose and lipid metabolism with anti-obesity and anti-diabetic properties. Thus, apelin appears as a promising therapeutic target in metabolic disorders.

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Authors and Affiliations

  1. Inserm U1048 I2MC,  , 1 avenue Jean Poulhès BP 84 225, 31432, Toulouse Cedex 4, France

    Philippe Valet

  2. INSERM U 1048 I2MC, 1 Ave J. Poulhès BP 84 225, 31432, Toulouse Cedex 4, France

    Isabelle Castan-laurell, Cédric Dray & Claude Knauf

Authors
  1. Isabelle Castan-laurell
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  2. Cédric Dray
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  3. Claude Knauf
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  4. Philippe Valet
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Correspondence to Philippe Valet .

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Editors and Affiliations

  1. Rue de la Chine 4, Paris, 75020, France

    Jean-Philippe Bastard

  2. Hôpital Saint-Antoine, Paris, France

    Bruno Fève

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Castan-laurell, I., Dray, C., Knauf, C., Valet, P. (2013). Apelin Metabolic Functions. In: Bastard, JP., Fève, B. (eds) Physiology and Physiopathology of Adipose Tissue. Springer, Paris. https://doi.org/10.1007/978-2-8178-0343-2_14

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  • DOI: https://doi.org/10.1007/978-2-8178-0343-2_14

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  • Print ISBN: 978-2-8178-0342-5

  • Online ISBN: 978-2-8178-0343-2

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