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Phyllodes tumours of the breast

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Management of Rare Adult Tumours

Abstract

Phyllodes tumours of the breast are rare tumours, accounting for 0.3–0.9% of breast tumours, and 2–3% of fibroepithelial tumours of the breast [3]. Phyllodes tumours have been described since 1982. The World Health Organization (WHO) proposed a classification with three distinct types: benign, borderline and malignant phyllodes tumours [11]. The pathological features classically used to distinguish these three categories are stromal cellularity, cell pleiomorphism, number of mitoses, margins, stromal pattern, and stromal differentiation. It is interesting to notice that malignant tumours have sarcomatous features with a metastatic potential, and although controversial, their prognosis is probably similar to that of non-phyllodes sarcomas of the breast [12]. The management of phyllodes tumours is mainly surgical, but controversies still remain concerning the type of surgery — conservative or not — especially for borderline and malignant forms, and about the role of adjuvant treatments (such as radiation therapy and chemotherapy). We propose to discuss these different points.

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© 2009 Springer-Verlag France, Paris

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Bousquet, G., Bonneterre, J., Belkacémi, Y. (2009). Phyllodes tumours of the breast. In: Belkacémi, Y., Mirimanoff, RO., Ozsahin, M. (eds) Management of Rare Adult Tumours. Springer, Paris. https://doi.org/10.1007/978-2-287-92246-6_41

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  • DOI: https://doi.org/10.1007/978-2-287-92246-6_41

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-92245-9

  • Online ISBN: 978-2-287-92246-6

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