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Abstrait

La population des greffés d’organe ne cesse de croître en raison d’un allongement régulier de leur survie àlong terme. Il existe maintenant de nombreux patients vivant depuis plus de 20 ans grâce àun greffon, la survie des plus anciens approchant 18, 27 et 40 ans après greffe hépatique, cardiaque et rénale, respectivement. Le bon fonctionnement du greffon nécessite la prise d’un traitement immunosuppresseur àvie induisant une nette augmentation du risque de cancers parmi lesquels les carcinomes cutanés sont les plus fréquents. Ils consistent en carcinomes cutanés (95% des cas), mais aussi en tumeurs variées telles la maladie de Kaposi, le mélanome, les cancers anogénitaux et d’autres tumeurs plus rares comme le carcinome àcellules de Merkel ou le fibroxanthome atypique.

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Euvrard, S., Kanitakis, J., Claudy, A. (2009). Cancers cutanés après transplantation d’organe. In: Manifestations dermatologiques des maladies du système hématopoïétique et oncologie dermatologique. Springer, Paris. https://doi.org/10.1007/978-2-287-72092-5_19

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