Abstrait
Le phénomène ďangiogenèse, formation de nouveaux vaisseaux à partir de vaisseaux existants, est une étape clé dans le développement des tumeurs. En effet, ľapport des éléments nutritifs se fait uniquement par diffusion passive pour les tumeurs de moins de 2 mm. Au-delà de cette taille, la création ďun réseau de néovaisseaux induit par la sécrétion de substances angiogéniques sécrétées par les cellules tumorales est nécessaire pour que la croissance tumorale se poursuive. La création de ce nouveau réseau vasculaire est également responsable ďune augmentation du potentiel invasif des tumeurs (1, 2, 3).
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Lassau, N., Chami, L., Péronneau, P. (2007). Ľimagerie de contraste ultrasonore pour ľévaluation précoce des thérapeutiques ciblées. In: Échographie de contraste. Springer, Paris. https://doi.org/10.1007/978-2-287-33297-5_6
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