Abstract
Properties of the ideal antihypertensive agent are given in Fig. 3.1. These properties are difficult to achieve with monotherapy; therefore, low doses of complementary drugs have been combined in an attempt to create a treatment for hypertension that is closer to the ideal. Administration of two complementary antihypertensive drugs in combination is always associated with greater efficacy than uptitration of an individual antihypertensive agent and provides an improved adverse event profile compared with monotherapy.
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Neutel, J. (2011). Advantages of Combination Therapy Compared with Monotherapy. In: Combination Therapy in Hypertension. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-908517-28-9_3
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DOI: https://doi.org/10.1007/978-1-908517-28-9_3
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