Abstract
Bone is a dynamic living tissue composed of metabolically active cells integrated into a rigid framework. The main constituents of bone are an organic matrix and a complex crystalline salt. The combination of soft collagen overlaid with hard mineral creates a structure that is flexible yet resilient to stress.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Kanis JA. Osteoporosis. Oxford: Blackwell Science; 1997.
World Health Organization (WHO). Prevention and management of osteoporosis. report of a WHO scientific group. WHO Technical Report Series 921. Geneva: WHO, 2003.
Hofbauer LC, Schoppet M. Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA 2004;292:490–5.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Healthcare, a part of Springer Science+Business Media
About this chapter
Cite this chapter
Reid, D.M. (2011). Pathophysiology. In: Handbook of Osteoporosis. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-908517-10-4_2
Download citation
DOI: https://doi.org/10.1007/978-1-908517-10-4_2
Publisher Name: Springer Healthcare, Tarporley
Print ISBN: 978-1-907673-07-8
Online ISBN: 978-1-908517-10-4
eBook Packages: MedicineMedicine (R0)