Skip to main content

Impact of Cardiopulmonary Bypass on Pulmonary Hemodynamic Variables

  • Chapter
  • First Online:
Principles of Pulmonary Protection in Heart Surgery
  • 1041 Accesses

Abstract

Ischemia reperfusion can be the triggering factor of lung injury; subsequently, high pulmonary vascular resistance (PVR) is a crucial risk factor of lung injury after cardiopulmonary bypass (CPB).1

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Suzuki T, Fukuda T, Inoue Y, Aki A, Cho Y. Effectiveness of continuous pulmonary perfusion during total cardiopulmonary bypass to prevent lung reperfusion injury. Nippon Kyobu Geka Gakkai Zasshi. 1997;45(1):31-36.

    PubMed  CAS  Google Scholar 

  2. Lamarche Y, Gagnon J, Malo O, Blaise G, Carrier M, Perrault LP. Ventilation prevents pulmonary endothelial dysfunction and improves oxygenation after cardiopulmonary bypass without aortic cross-clamping. Eur J Cardiothorac Surg. 2004;26(3):554-563.

    Article  PubMed  Google Scholar 

  3. Nyhan D, Gaine S, Hales M, et al. Pulmonary vascular endothelial responses are differentially modulated after cardiopulmonary bypass. J Cardiovasc Pharmacol. 1999;34(4):518-525.

    Article  PubMed  CAS  Google Scholar 

  4. Onorati F, Cristodoro L, Bilotta M, et al. Intraaortic balloon pumping during cardioplegic arrest preserves lung function in patients with chronic obstructive pulmonary disease. Ann Thorac Surg. 2006;82(1):35-43.

    Article  PubMed  Google Scholar 

  5. Kuratani T, Matsuda H, Sawa Y, Kaneko M, Nakano S, Kawashima Y. Experimental study in a rabbit model of ischemia-reperfusion lung injury during cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1992;103(3):564-568.

    PubMed  CAS  Google Scholar 

  6. Wagner EM, Blosser S, Mitzner W. Bronchial vascular contribution to lung lymph flow. J Appl Physiol. 1998;85(6):2190-2195.

    PubMed  CAS  Google Scholar 

  7. Mendler N, Heimisch W, Schad H. Pulmonary function after biventricular bypass for autologous lung oxygenation. Eur J Cardiothorac Surg. 2000;17:325-330.

    Article  PubMed  CAS  Google Scholar 

  8. Schlensak C, Beyersdorf F. Lung injury during CPB: pathomechanisms and clinical relevance. Interact Cardiovasc Thorac Surg. 2005;4(5):381-382.

    Article  PubMed  Google Scholar 

  9. Shivaprakasha K, Rameshkumar I, Kumar RK, et al. New technique of right heart bypass in congenital heart surgery with autologous lung as oxygenator. Ann Thorac Surg. 2004;77(3):988-993.

    Article  PubMed  Google Scholar 

  10. Pepino P, Oliviero P, Petteruti F, Tommaso L, Monaco M, Stassano P. Left heart pump-assisted beating heart coronary surgery in high-risk patients. Asian Cardiovasc Thorac Ann. 2008;16(2):159-161.

    PubMed  Google Scholar 

  11. Sievers HH, Freund-Kaas C, Eleftheriadis S, et al. Lung protection during total cardiopulmonary bypass by isolated lung perfusion: preliminary results of a novel perfusion strategy. Ann Thorac Surg. 2002;74:1167-1172.

    Article  PubMed  Google Scholar 

  12. Gabriel EA, Locali RF, Matsuoka PK, et al. Lung perfusion during cardiac surgery with cardiopulmonary bypass: is it necessary? Interact Cardiovasc Thorac Surg. 2008;7:1089-1095.

    Article  PubMed  Google Scholar 

  13. Carvalho EMF, Gabriel EA, Salerno TA. Pulmonary protection during cardiac surgery: systematic literature review. Asian Cardiovasc Thorac Ann. 2008;16:503-507.

    PubMed  Google Scholar 

  14. Halldorsson AO, Kronon M, Allen BS, et al. Controlled reperfusion prevents pulmonary injury after 24 hours of lung preservation. Ann Thorac Surg. 1998;66:877-885.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Edmo Atique Gabriel .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer London

About this chapter

Cite this chapter

Gabriel, E.A., Salerno, T. (2010). Impact of Cardiopulmonary Bypass on Pulmonary Hemodynamic Variables. In: Gabriel, E., Salerno, T. (eds) Principles of Pulmonary Protection in Heart Surgery. Springer, London. https://doi.org/10.1007/978-1-84996-308-4_24

Download citation

  • DOI: https://doi.org/10.1007/978-1-84996-308-4_24

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84996-307-7

  • Online ISBN: 978-1-84996-308-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics