Abstract
Rhythmic behavior represents one of the most striking dynamical phenomena in biological systems. The biological rhythms, including neural, cardiac, glycolytic, mitotic, hormonal, circadian rhythms, and rhythms in ecology and epidemiology, with periods ranging from seconds to years, play important roles in many processes (Goldbeter 1997). Such dynamical phenomena arise from interplay of cellular components and are typically generated by negative feedback loops (Dunlap 1999). From both theoretical and experimental viewpoints, it is still a great challenge to model, analyze, and further predict oscillatory phenomena in various living organisms. Oscillations, particularly periodic oscillations, are widely used in engineering control systems as central clocks to synchronize various elements with periodic behavior. Many multicellular organisms also adopt variations of cellular clocks to coordinate their behavior over the course of the day–night cycle. Models and theoretical approaches are essential for gaining understanding of the principles underlying these rhythmic or oscillating processes.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Rights and permissions
Copyright information
© 2010 Springer-Verlag London Limited
About this chapter
Cite this chapter
(2010). Design of Synthetic Oscillating Networks. In: Modeling Biomolecular Networks in Cells. Springer, London. https://doi.org/10.1007/978-1-84996-214-8_7
Download citation
DOI: https://doi.org/10.1007/978-1-84996-214-8_7
Publisher Name: Springer, London
Print ISBN: 978-1-84996-213-1
Online ISBN: 978-1-84996-214-8
eBook Packages: EngineeringEngineering (R0)