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Use of Cord Blood in Regenerative Medicine

  • David T. Harris
Chapter

Abstract

It is estimated that up to 128 million individuals might benefit from regenerative medicine therapy, or almost one in three individuals in the USA. Multipotent stem cells are easily available in large numbers in umbilical cord blood (CB), and may be the best alternative to embryonic stem (ES) cells. CB stem cells are capable of giving rise to hematopoietic, epithelial, endothelial, and neural tissues both in vitro and in vivo. Thus, CB stem cells are amenable to treat a wide variety of diseases including cardiovascular, ophthalmic, orthopedic, neurological, and endocrine diseases. Examples of these usages currently in clinical trials include applications that affect the nervous and endocrine system, including cerebral palsy and type I diabetes. The numbers of such individuals affected with each of these diseases are estimated to be 10,000 annually. A summary of the initial beneficial results from such clinical trials using autologous CB stem cells will be presented.

Keywords

Stem Cell Traumatic Brain Injury Spinal Cord Injury Cord Blood Cerebral Palsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

CB

Cord blood

CP

Cerebral palsy

T1D

Type I diabetes.

Notes

Acknowledgments

The funding by The Jerome Lejeune Foundation is gratefully acknowledged.

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Copyright information

© Springer London 2011

Authors and Affiliations

  1. 1.Department of ImmunobiologyThe University of ArizonaTucsonUSA

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