Umbilical Cord and Its Blood: A Perspective on Its Current and Potential Use in Ophthalmology

  • Kyung-Chul YoonEmail author


Recently, umbilical cord blood has been used in the treatment of various ocular surface diseases in ophthalmology. Umbilical cord blood contains essential tear components, growth factors, and neurotrophic factors such as epidermal growth factor, vitamin A, transforming growth factor-b, substance P, insulin-like growth factor, and nerve growth factor. Umbilical cord serum can provide basic nutrients for epithelial renewal and facilitate the proliferation, migration, and differentiation of the ocular surface epithelium. Serum eye drops made from umbilical cord blood can be used safely and effectively for the treatment of severe dry eye with or without Sjögren’s syndrome, ocular complications in graft-versus-host disease, persistent epithelial defects, and neurotrophic keratopathy.


Umbilical Cord Blood Ocular Surface Autologous Serum Epithelial Defect Ocular Surface Disease 
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Copyright information

© Springer London 2011

Authors and Affiliations

  1. 1.Department of OphthalmologyChonnam National University Medical School and HospitalGwang-JuSouth Korea

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