Implications of Feto-maternal Cell Transfer in Normal Pregnancy

  • Carolyn TroegerEmail author
  • Olav Lapaire
  • Xiao Yan Zhong
  • Wolfgang Holzgreve


Traditionally, the placenta has been thought to be a well-built barrier that separates the genetically different mother and offspring. This has been studied and discussed by K.E. von Baer already in 1828 when he found separate vascular beds in dogs.1 In the following years, it has been suggested that there is communication between the placenta and the host mother, because syncytiotrophoblasts have been found in the lungs of women who died of eclampsia.2 Transplacental fetal “bleeding” was recognized only in cases with a significant placental trauma, e.g., car accident, amniocentesis, chorionic villous sampling, termination of pregnancy, and external version done for breech presentation.


Maternal Blood Fetal Cell HELLP Syndrome Maternal Cell Microchimeric Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer London 2011

Authors and Affiliations

  • Carolyn Troeger
    • 1
    Email author
  • Olav Lapaire
  • Xiao Yan Zhong
  • Wolfgang Holzgreve
  1. 1.Laboratory for Prenatal MedicineUniversity Women´s HospitalBaselSwitzerland

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