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Sleep, Stress, and Heart Disease

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Stress and Cardiovascular Disease

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Abstract

It is estimated that sleep problems affect around 20% of the adult population in the Western countries.1,2 It has been shown that the short-term consequences of sleep problems lead to adverse physiological changes,3 as well as to long-term health consequences. In experimental and epidemiological studies, both short and long sleep hours have been related to hypertension,4 type-2 diabetes,5,6 increased body mass index (BMI),7 alterations in blood lipids,8 and inflammatory markers9 – all factors known to increase the risk of cardiovascular disease.

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References

  1. NSF. Sleep in America Poll. Washington DC: National Sleep Foundation; 2002.

    Google Scholar 

  2. Ohayon MM, Carskadon MA, Guilleminault C, Vitiello MV. Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan. Sleep. 2004;27(7):1255-1273.

    PubMed  Google Scholar 

  3. Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet. 1999;354:1435-1439.

    Article  PubMed  CAS  Google Scholar 

  4. Gangwisch JE, Heymsfield SB, Boden-Albala B, et al. Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination Survey. Hypertension. 2006;47(5):833-839.

    Article  PubMed  CAS  Google Scholar 

  5. Gangwisch JE, Heymsfield SB, Boden-Albala B, et al. Sleep duration as a risk factor for ­diabetes incidence in a large U.S. sample. Sleep. 2007;30(12):1667-1673.

    PubMed  Google Scholar 

  6. Yaggi HK, Araujo AB, McKinlay JB. Sleep duration as a risk factor for the development of type 2 diabetes. Diabetes Care. 2006;29(3):657-661.

    Article  PubMed  Google Scholar 

  7. Stranges S, Cappuccio FP, Kandala NB, et al. Cross-sectional versus prospective associations of sleep duration with changes in relative weight and body fat distribution: the Whitehall II Study. Am J Epidemiol. 2008;167(3):321-329.

    Article  PubMed  Google Scholar 

  8. Vgontzas AN, Bixler EO, Chrousos GP. Sleep apnea is a manifestation of the metabolic ­syndrome. Sleep Med Rev. 2005;9:211-224.

    Article  PubMed  Google Scholar 

  9. Vgontzas AN, Zoumakis E, Bixler EO, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab. 2004;89(5):2119-2126.

    Article  PubMed  CAS  Google Scholar 

  10. Greenland P, Knoll MD, Stamler J, et al. Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. JAMA. 2003;290(7):891-897.

    Article  PubMed  Google Scholar 

  11. Gallicchio L, Kalesan B. Sleep duration and mortality: a systematic review and meta-analysis. J Sleep Res. 2009;18:148-158.

    Article  PubMed  Google Scholar 

  12. McEwen BS. Sleep deprivation as a neurobiologic and physiologic stressor: allostasis and allostatic load [Suppl 2]. Metabolism. 2006;55:S20-S23.

    Article  PubMed  CAS  Google Scholar 

  13. Carskadon MA, Dement WC. Normal human sleep: an overview. In: Kryger MH, Roth T, Dement WC, eds. Principles and practice of sleep medicine. 3rd ed. Philadelphia: W.B. Saunders Company; 2000:15-25.

    Google Scholar 

  14. Rechtschaffe A, Kales A. A manual of standardized terminology, techniques and scoring ­system for sleep stages of human subjects. Bethesda: US Department of Health, Education and Welfare, Public Health Service; 1968.

    Google Scholar 

  15. Borbély AA. A two-process model of sleep regulation. Hum Neurobiol. 1982;1:195-204.

    PubMed  Google Scholar 

  16. Åkerstedt T, Folkard S, Portin C. Predictions from the three-process model of alertness. Aviat Space Environ Med. 2004;75:A75-A83.

    PubMed  Google Scholar 

  17. Porkka-Heiskanen T. Adenosine in sleep and wakefulness. Ann Med. 1999;31(2):125-129.

    Article  PubMed  CAS  Google Scholar 

  18. Saper CB, Chou TC, Scammell TE. The sleep switch: hypothalamic control of sleep and ­wakefulness. Trends Neurosci. 2001;24(12):726-731.

    Article  PubMed  CAS  Google Scholar 

  19. Webb WB, Agnew HW Jr. Stage 4 sleep: influence of time course variables. Science. 1971;174:1354-1356.

    Article  PubMed  CAS  Google Scholar 

  20. Horne JA. Functional aspects of human slow wave sleep. In: Wauquier A, Dugovic C, Radulovacki M, eds. Slow Wave Sleep. Physiological, Pathophysiological, and Functional Aspects. New York: Raven Press; 1989:109-119.

    Google Scholar 

  21. Saper CB, Lu J, Chou TC, Gooley J. The hypothalamic integrator for circadian rhythms. Trends Neurosci. 2005;28(3):152-157.

    Article  PubMed  CAS  Google Scholar 

  22. Foret J, Lantin G. The sleep of train drivers: an example of the effects of irregular work schedules on sleep. In: Colquhoun WP, ed. Aspects of Human Efficiency. Diurnal Rhythm and Loss of Sleep. London: The English Universities Press Ltd; 1972:273-281.

    Google Scholar 

  23. Åkerstedt T, Gillberg M. The circadian variation of experimentally displaced sleep. Sleep. 1981;4:159-169.

    PubMed  Google Scholar 

  24. Czeisler CA, Weitzman ED, Moore-Ede MC, Zimmerman JC, Knauer RS. Human sleep: its duration and organization depend on its circadian phase. Science. 1980;210:1264-1267.

    Article  PubMed  CAS  Google Scholar 

  25. Åkerstedt T, Gillberg M. A dose-response study of sleep loss and spontaneous sleep termination. Psychophysiology. 1986;23:293-297.

    Article  PubMed  Google Scholar 

  26. McEwen BS, Wingfield JC. The concept of allostasis in biology and biomedicine. Horm Behav. 2003;43(1):2-15.

    Article  PubMed  Google Scholar 

  27. McEwen BS. Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders. Ann N Y Acad Sci. 2004;1032:1-7.

    Article  PubMed  Google Scholar 

  28. Ancoli-Israel S, Roth T. Characteristics of insomnia in the United States: results of the 1991 National Sleep Foundation survey. I. Sleep. 1999;22 Suppl.2:S347-S353.

    PubMed  Google Scholar 

  29. Morphy H, Dunn M, Lewis M, Boardman HF, Croft PR. Epidemiology of insomnia: a ­longitudinal study in a UK population. Sleep. 2007;30(3):274-280.

    PubMed  Google Scholar 

  30. Ribet C, Derriennic F. Age, working conditions, and sleep disorders: a longitudinal analysis in the French Cohort E.S.T.E.V. Sleep. 1999;22:491-504.

    PubMed  CAS  Google Scholar 

  31. Urponen H, Vuori I, Hasan J, Partinen M. Self-evaluations of factors promoting and disturbing sleep: an epidemiological survey in Finland. Soc Sci Med. 1988;26:443-450.

    Article  PubMed  CAS  Google Scholar 

  32. Åkerstedt T, Fredlund P, Gillberg M, Jansson B. Work load and work hours in relation to disturbed sleep and fatigue in a large representative sample. J Psychosom Res. 2002;53:585-588.

    Article  PubMed  Google Scholar 

  33. Morin CM, Rodrigue S, Ivers H. Role of stress, arousal, and coping skills in primary insomnia. Psychosom Med. 2003;65:259-267.

    Article  PubMed  Google Scholar 

  34. Cernovsky ZZ. Life stress measures and reported frequency of sleep disorders. Percept Mot Skills. 1984;58:39-49.

    Article  PubMed  CAS  Google Scholar 

  35. Jansson M, Linton SJ. Psychosocial work stressors in the development and maintenance of insomnia: a prospective study. J Occup Health Psychol. 2006;11(3):241-248.

    Article  PubMed  Google Scholar 

  36. Holdstock TL, Verschoor GJ. Student sleep patterns before, during and after an examination period. J Psychol. 1974;4:16-24.

    Google Scholar 

  37. Åkerstedt T. Sleep and stress. In: Peter JH, Podszus T, von Wichert P, eds. Sleep Related Disorders and Internal Diseases. Heidelberg: Springer; 1987:183-191.

    Chapter  Google Scholar 

  38. Drake C, Richardson G, Roehrs T, Scofield H, Roth T. Vulnerability to stress-related sleep disturbance and hyperarousal. Sleep. 2004;27:285-291.

    PubMed  Google Scholar 

  39. Partinen M, Eskelinen L, Tuomi K. Complaints of insomnia in different occupations. Scand J Work Environ Health. 1984;10:467-469.

    Article  PubMed  CAS  Google Scholar 

  40. Geroldi C, Frisoni GB, Rozzini R, De Leo D, Trabucchi M. Principal lifetime occupation and sleep quality in the elderly. Gerontology. 1996;42:163-169.

    Article  PubMed  CAS  Google Scholar 

  41. Kuppermann M, Lubeck DP, Mazonson PD, et al. Sleep problems and their correlates in a working population. J Gen Intern Med. 1995;10:25-32.

    Article  PubMed  CAS  Google Scholar 

  42. Bixler EO, Kales A, Soldatos CR. Sleep disorders encountered in medical practice: a national survey of physicians. Behav Med. 1979;3:1-6.

    Google Scholar 

  43. Åkerstedt T, Knutsson A, Westerholm P, Theorell T, Alfredsson L, Kecklund G. Sleep ­disturbances, work stress and work hours. A cross-sectional study. J Psychosom Res. 2002;53:741-748.

    Article  PubMed  Google Scholar 

  44. Harvey AG, Tang NK, Browning L. Cognitive approaches to insomnia. Clin Psychol Rev. 2005;25(5):593-611.

    Article  PubMed  Google Scholar 

  45. Hall M, Buysse DJ, Nowell PD, et al. Symptoms of stress and depression as correlates of sleep in primary Insomnia. Psychosom Med. 2000;62:227-230.

    PubMed  CAS  Google Scholar 

  46. Haynes SN, Adams A, Franzen M. The effects of presleep stress on sleep-onset insomnia. J Abnorm Psychol. 1981;90:601-606.

    Article  PubMed  CAS  Google Scholar 

  47. Tang NKY, Harvey AG. Effects of cognitive arousal and physiological arousal on sleep ­perception. Sleep. 2004;27:69-78.

    PubMed  Google Scholar 

  48. Kecklund G, Åkerstedt T. Objective components of individual differences in subjective sleep quality. J Sleep Res. 1997;6:217-220.

    Article  Google Scholar 

  49. Kecklund G, Åkerstedt T, Lowden A. Morning work: effects of early rising on sleep and ­alertness. Sleep. 1997;20(3):215-223.

    PubMed  CAS  Google Scholar 

  50. Akerstedt T, Kecklund G, Axelsson J. Impaired sleep after bedtime stress and worries. Biol Psychol. 2007;76(3):170-173.

    Article  PubMed  Google Scholar 

  51. Askenasy JJM, Lewin I. The impact of missile warfare on self-reported sleep quality. Part 1. Sleep. 1996;19:47-51.

    PubMed  CAS  Google Scholar 

  52. Davidson L, Fleming R, Baum A. Chronic stress, catecholamines, and sleep disturbance at three Mile Island. J Human Stress. 1987;13:75-83.

    Article  PubMed  CAS  Google Scholar 

  53. Reynolds CF III, Hoch CC, Buysse DJ, et al. Sleep after spousal bereavement: a study of recovery from stress. Biol Psychiatry. 1993;34:791-797.

    Article  PubMed  Google Scholar 

  54. Nordin M, Knutsson A, Sundbom E. Is disturbed sleep a mediator in the association between social support and myocardial infarction? J Health Psychol. 2008;13(1):55-64.

    Article  PubMed  Google Scholar 

  55. Fabsitz RR, Sholinsky P, Goldberg J. Correlates of sleep problems among men: the Vietnam era twin registry. J Sleep Res. 1997;6:50-60.

    Article  PubMed  CAS  Google Scholar 

  56. Dow BM, Kelsoe JR, Gillin JC. Sleep and dreams in Vietnam PTSD and depression. Biol Psychiatry. 1996;39:42-50.

    Article  PubMed  CAS  Google Scholar 

  57. Mellman TA, Nolan B, Hebding J, Kulick-Bell R, Dominguez R. A polysomnographic comparison of veterans with combat-related PTSD, depressed men, and non-ill controls. Sleep. 1997;20:46-51.

    PubMed  CAS  Google Scholar 

  58. Pillar G, Malhotra A, Lavie P. Post-traumatic stress disorder and sleep – what a nightmare! Sleep Med Rev. 2000;4:183-200.

    Article  PubMed  Google Scholar 

  59. Ross RJ, Ball WA, Dinges DF, et al. Motor dysfunction during sleep in posttraumatic stress disorder. Sleep. 1994;17:723-732.

    PubMed  CAS  Google Scholar 

  60. AASM. ICSD – International Classification of Sleep Disorders, Revised: Diagnostic and Coding Manual. Chicago: American Academy of Sleep Medicine; 2005.

    Google Scholar 

  61. APA. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. (DSM-IV). Washington DC: American Psychiatric Association; 1994.

    Google Scholar 

  62. Lichstein KL, Durrence HH, Taylor DJ, Bush AJ, Riedel BW. Quantitative criteria for ­insomnia. Behav Res Ther. 2003;41(4):427-445.

    Article  PubMed  CAS  Google Scholar 

  63. Ohayon M, Caulet M, Priest R, Guilleminault C. DSM-IV and ICSD-90 insomnia symptoms and sleep dissatisfaction. Br J Psychiatry. 1997;171:382-388.

    Article  PubMed  CAS  Google Scholar 

  64. Jansson-Frojmark M, Linton SJ. The course of insomnia over one year: a longitudinal study in the general population in Sweden. Sleep. 2008;31(6):881-886.

    PubMed  Google Scholar 

  65. Roth T, Drake C. Evolution of insomnia: current status and future direction. Sleep Med. 2004;5(suppl 1):S23-S30.

    Article  PubMed  Google Scholar 

  66. Ohayon MM, Guilleminault C, Paiva T, et al. An international study on sleep disorders in the general population: methosological aspects of the use of the sleep-EVAL system. Sleep. 1997;20:1086-1092.

    PubMed  CAS  Google Scholar 

  67. Sateia M, Doghramji K, Hauri PJ, Morin CM. Evaluation of chronic insomnia. Sleep. 2000;23:243-263.

    PubMed  CAS  Google Scholar 

  68. Adam K, Tomeny M, Oswald I. Physiological and psychological differences between good and poor sleepers. J Psychiatr Res. 1986;20(4):301-316.

    Article  PubMed  CAS  Google Scholar 

  69. Bonnet MH, Arand DL. Heart rate variability in insomniacs and matched normal sleepers. Psychosom Med. 1998;60:610-615.

    PubMed  CAS  Google Scholar 

  70. Monroe L. Psychological and physiological differences between good and poor sleepers. J Abnorm Psychol. 1967;72:255-264.

    Article  PubMed  CAS  Google Scholar 

  71. Perlis ML, Merica H, Smith MT, Giles DE. Beta EEG activity and insomnia. Sleep Med Rev. 2001;5(5):365-376.

    Article  Google Scholar 

  72. Bonnet MH, Arand DL. Insomnia, metabolic rate and sleep restoration. J Intern Med. 2003;254(1):23-31.

    Article  PubMed  CAS  Google Scholar 

  73. Wong KK, Marshall NS, Grunstein RR, Dodd MJ, Rogers NL. Comparing the neurocognitive effects of 40 h sustained wakefulness in patients with untreated OSA and healthy controls. J Sleep Res. 2008;17:322-330.

    Article  PubMed  Google Scholar 

  74. Terán-Santos J, Jimnénez-Gómez A, Cordero-Guevara J. The association between sleep apnea and the risk of traffic accidents. N Engl J Med. 1999;24:847-851.

    Article  Google Scholar 

  75. Lopez-Jimenez F, Somers VK. Stress measures linking sleep apnea, hypertension and ­diabetes–AHI vs arousals vs hypoxemia. Sleep. 2006;29(6):743-744.

    PubMed  Google Scholar 

  76. Lavie L. Sleep apnea syndrome, endothelial dysfunction, and cardiovascular morbidity. Sleep. 2004;27:1053-1055.

    PubMed  Google Scholar 

  77. Mulgrew AT, Ryan CF, Fleetham JA, et al. The impact of obstructive sleep apnea and daytime sleepiness on work limitation. Sleep Med. 2007;9(1):42-53.

    Article  PubMed  CAS  Google Scholar 

  78. Zee PC, Manthena P. The brain’s master circadian clock: implications and opportunities for therapy of sleep disorders. Sleep Med Rev. 2007;11(1):59-70.

    Article  PubMed  Google Scholar 

  79. Wolk R, Gami AS, Garcia-Touchard A, Somers VK. Sleep and cardiovascular disease. Curr Probl Cardiol. 2005;30(12):625-662.

    Article  PubMed  Google Scholar 

  80. Otto ME, Svatikova A, Barretto RB, et al. Early morning attenuation of endothelial function in healthy humans. Circulation. 2004;109(21):2507-2510.

    Article  PubMed  Google Scholar 

  81. Tofler GH, Brezinski D, Schafer AI, et al. Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Engl J Med. 1987;316(24):1514-1518.

    Article  PubMed  CAS  Google Scholar 

  82. Muller JE, Stone PH, Zoltan GT, et al. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med. 1985;313:1315-1322.

    Article  PubMed  CAS  Google Scholar 

  83. Charkoudian N, Rabbitts JA. Sympathetic neural mechanisms in human cardiovascular health and disease. Mayo Clin Proc. 2009;84(9):822-830.

    Article  PubMed  Google Scholar 

  84. Mullington JM, Haack M, Toth M, Serrador JM, Meier-Ewert HK. Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation. Prog Cardiovasc Dis. 2009;51(4):294-302.

    Article  PubMed  CAS  Google Scholar 

  85. Gottlieb DJ, Redline S, Nieto FJ, et al. Association of usual sleep duration with hypertension: the Sleep Heart Health Study. Sleep. 2006;29(8):1009-1014.

    PubMed  Google Scholar 

  86. Vgontzas AN, Liao D, Bixler EO, Chrousos GP, Vela-Bueno A. Insomnia with objective short sleep duration is associated with a high risk for hypertension. Sleep. 2009;32(4):491-497.

    PubMed  Google Scholar 

  87. Steiger A. Sleep and the hypothalamo-pituitary-adrenocortical system. Sleep Med Rev. 2002;6(2):125-138.

    Article  PubMed  Google Scholar 

  88. Steiger A, Antonijevic IA, Bohlhalter S, Frieboes RM, Friess E, Murck H. Effects of hormones on sleep. Horm Res. 1998;49:125-130.

    Article  PubMed  CAS  Google Scholar 

  89. Ekstedt M, Åkerstedt T, Söderström M. Microarousals during sleep are associated with increased levels of lipids, cortisol, and blood pressure. Psychosom Med. 2004;66:925-931.

    Article  PubMed  CAS  Google Scholar 

  90. Van Cauter E, Latta F, Nedeltcheva A, et al. Reciprocal interactions between the GH axis and sleep. Growth Horm IGF Res. 2004;14:S10-S17.

    Article  PubMed  CAS  Google Scholar 

  91. Knutson KL, Spiegel K, Penev P, Van Cauter E. The metabolic consequences of sleep deprivation. Sleep Med Rev. 2007;11(3):163-178.

    Article  PubMed  Google Scholar 

  92. Hall MH, Muldoon MF, Jennings JR, Buysse DJ, Flory JD, Manuck SB. Self-reported sleep duration is associated with the metabolic syndrome in midlife adults. Sleep. 2008;31(5):635-643.

    PubMed  Google Scholar 

  93. Patel SR, Hu FB. Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring). 2008;16(3):643-653.

    Article  Google Scholar 

  94. Tasali E, Leproult R, Spiegel K. Reduced sleep duration or quality: relationships with insulin resistance and type 2 diabetes. Prog Cardiovasc Dis. 2009;51(5):381-391.

    Article  PubMed  CAS  Google Scholar 

  95. Nilsson P, Rööst M, Engström G, Hedblad B, Janzon L, Berglund G. Incidence of diabetes in middle-aged men is related to resting heart rate and difficulties to fall asleep. (Abstract). Paper presented at: the 7th International Congress of Behavioural Medicine; 2002; Helsinki.

    Google Scholar 

  96. Nilsson PM, Rööst M, Engström G, Hedblad B, Berglund G. Incidence of diabetes in middle-aged men is related to sleep disturbances. Diabetes Care. 2004;27:2464-2469.

    Article  PubMed  Google Scholar 

  97. Bryant PA, Trinder J, Curtis N. Sick and tired: does sleep have a vital role in the immune ­system. Nat Rev Immunol. 2004;4:457-467.

    Article  PubMed  CAS  Google Scholar 

  98. Vgontzas AN, Papanicolaou DA, Bixler EO, Kales A, Tyson K, Chrousos GP. Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity. J Clin Endocrinol Metab. 1997;82(5):1313-1316.

    Article  PubMed  CAS  Google Scholar 

  99. Nilsson P, Nilsson J-Å, Hedblad B, Berglund G. Sleep disturbances in association with elevated pulse rate for the prediction of mortality – consequences of mental strain? J Intern Med. 2001;250:521-529.

    Article  PubMed  CAS  Google Scholar 

  100. Leineweber C, Kecklund G, Janszky I, Åkerstedt T, Orth-Gomér K. Poor sleep increases the prospective risk for recurrent events in middle-aged women with coronary disease. The Stockholm Female Coronary Risk Study. J Psychosom Res. 2003;54:121-127.

    Article  PubMed  Google Scholar 

  101. Appels A, Schouten E. Waking up exhausted as risk indicator of myocardial infarction. Am J Cardiol. 1991;68:395-398.

    Article  PubMed  CAS  Google Scholar 

  102. van Diest R, Appels AWPM. Sleep physiological characteristics of exhausted men. Psychosom Med. 1994;56:28-35.

    PubMed  Google Scholar 

  103. Melamed S, Shirom A, Toker S, Berliner S, Shapira I. Burnout and risk of cardiovascular disease: evidence, possible causal paths, and promising research directions. Psychol Bull. 2006;132(3):327-353.

    Article  PubMed  Google Scholar 

  104. Kripke DF, Simons RN, Garfinkel L, Hammond EC. Short and long sleep and sleeping pills. Arch Gen Psychiatry. 1979;36:103-116.

    Article  PubMed  CAS  Google Scholar 

  105. Kripke DF, Garfinkel L, Wingard DL, Klauber MR, Marler MR. Mortality associated with sleep duration and insomnia. Arch Gen Psychiatry. 2002;59:131-136.

    Article  PubMed  Google Scholar 

  106. Ferrie JE, Shipley MJ, Cappuccio FP, et al. A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohort. Sleep. 2007;30(12):1659-1666.

    PubMed  Google Scholar 

  107. Hublin C, Partinen M, Koskenvuo M, Kaprio J. Sleep and mortality: a population-based 22-year follow-up study. Sleep. 2007;30(10):1245-1253.

    PubMed  Google Scholar 

  108. Amagai Y, Ishikawa S, Gotoh T, et al. Sleep duration and mortality in Japan: the Jichi Medical School Cohort Study. J Epidemiol. 2004;14(4):124-128.

    Article  PubMed  Google Scholar 

  109. Ayas NT, White DP, Manson JE, et al. A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med. 2003;163(2):205-209.

    Article  PubMed  Google Scholar 

  110. Empana JP, Dauvilliers Y, Dartigues JF, et al. Excessive daytime sleepiness is an independent risk indicator for cardiovascular mortality in community-dwelling elderly: the three city study. Stroke. 2009;40(4):1219-1224.

    Article  PubMed  Google Scholar 

  111. Patel SR, Ayas NT, Malhotra MR, et al. A prospective study of sleep duration and mortality risk. Sleep. 2004;27:440-444.

    PubMed  Google Scholar 

  112. Heslop P, Smith GD, Metcalfe C, Macleod J, Hart C. Sleep duration and mortality: the effect of short or long sleep duration on cardiovascular and all-cause mortality in working men and women. Sleep Med. 2002;3(4):305-314.

    Article  PubMed  Google Scholar 

  113. Meisinger C, Heier M, Lowel H, Schneider A, Doring A. Sleep duration and sleep complaints and risk of myocardial infarction in middle-aged men and women from the general ­population: the MONICA/KORA Augsburg cohort study. Sleep. 2007;30(9):1121-1127.

    PubMed  Google Scholar 

  114. Mallon L, Broman JE, Hetta J. Sleep complaints predict coronary artery disease mortality in males: a 12-year follow-up study of a middle-aged Swedish population. J Intern Med. 2002;251(3):207-216.

    Article  PubMed  CAS  Google Scholar 

  115. Ekstedt M, Söderström M, Åkerstedt T, Nilsson J, Sondergaard H-P, Perski A. Disturbed sleep and fatigue in occupational burnout. Scand J Work Environ Health. 2006;32(2):121-131.

    Article  PubMed  Google Scholar 

  116. Gopalakrishnan P, Ragland MM, Tak T. Gender differences in coronary artery disease: review of diagnostic challenges and current treatment. Postgrad Med. 2009;121(2):60-68.

    Article  PubMed  Google Scholar 

  117. Wenger NK. Preventing cardiovascular disease in women: an update. Clin Cardiol. 2008;31(3):109-113.

    Article  PubMed  Google Scholar 

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  1. Stress Research Institute, Stockholm University, 106 91, Stockholm, Sweden

    Torbjörn Åkerstedt & Aleksander Perski

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  1. Torbjörn Åkerstedt
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Correspondence to Torbjörn Åkerstedt .

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Editors and Affiliations

  1. Karolinska Hospital, Dept. Clinical Pharmacology, Karolinska Institute, Stockholm, 171 76, Sweden

    Paul Hjemdahl

  2. St Georges Hospital Medical School, Dept. Psychology, University of London, Cranmer Terrace, London, SW17 0RE, United Kingdom

    Andrew Steptoe

  3. Sahlgrenska University Hospital/Östra, Göteborg, SE-416 85, Sweden

    Annika Rosengren

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Åkerstedt, T., Perski, A. (2011). Sleep, Stress, and Heart Disease. In: Hjemdahl, P., Steptoe, A., Rosengren, A. (eds) Stress and Cardiovascular Disease. Springer, London. https://doi.org/10.1007/978-1-84882-419-5_14

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