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Central Transmission: From Skin to Brain

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Pruritus

Abstract

Since 1660, itch has been defined as “an unpleasant sensation associated with the desire to scratch.”1 This definition encompasses both sensory and cognitive aspects of the itch experience. However, the manner in which this sensory stimulus transmits from the skin to the brain for processing has only recently been elucidated. This chapter will describe the flow of neural information that pertains to pruritus from the peripheral to the central nervous system.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA

    Tejesh Surendra Patel

  2. Departments of Dermatology and Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

    Gil Yosipovitch

Authors
  1. Tejesh Surendra Patel
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  2. Gil Yosipovitch
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Corresponding author

Correspondence to Tejesh Surendra Patel .

Editor information

Editors and Affiliations

  1. Dept. Dermatologie, CHU Brest, Brest, 29200, France

    Laurent Misery

  2. Medizinische Einrichtungen, Klinik und Poliklinik für, Universitätsklinikum Münster, Von-Esmarch-Str. 56, Münster, 48149, Germany

    Sonja Ständer

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Patel, T.S., Yosipovitch, G. (2010). Central Transmission: From Skin to Brain. In: Misery, L., Ständer, S. (eds) Pruritus. Springer, London. https://doi.org/10.1007/978-1-84882-322-8_4

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  • DOI: https://doi.org/10.1007/978-1-84882-322-8_4

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-321-1

  • Online ISBN: 978-1-84882-322-8

  • eBook Packages: MedicineMedicine (R0)

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