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Introduction to Hypermobility

  • Peter Beighton
  • Rodney Grahame
  • Howard Bird
Chapter

Abstract

The first clinical description of articular hypermobility is attributed to Hippocrates, who, in the fourth century B.C., described the Scythians, a race of Iranian horse-riding nomads inhabiting the region that now forms the Ukraine, as having humidity, flabbiness and atony such that they were unable to use their weapons. Their main problem in warfare was that hyperlaxity of the elbow and shoulder joints prevented them from drawing their bows effectively.

Keywords

Marfan Syndrome Joint Laxity Joint Hypermobility Generalise Joint Hypermobility Hypermobility Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Finkelstein H. Joint hypotonia. N Y Med J. 1916;104:942-943.Google Scholar
  2. 2.
    Key JA. Hypermobility of joints as a sex linked hereditary characteristic. JAMA. 1927;88:1710-1712.CrossRefGoogle Scholar
  3. 3.
    Massie WK, Howarth MB. Congenital dislocation of the hip. Part II. Results of an open reduction as seen in early adult period. J Bone Joint Surg Am. 1951;33:171-190.PubMedGoogle Scholar
  4. 4.
    Carter C, Wilkinson J. Persistent joint laxity and congenital dislocation of the hip. J Bone Joint Surg Br. 1964;46-B:40-45.Google Scholar
  5. 5.
    Carter C, Sweetnam R. Familial joint laxity and recurrent dislocation of the patella. J Bone Joint Surg Br. 1958;40-B:664-667.PubMedGoogle Scholar
  6. 6.
    Carter C, Sweetnam R. Recurrent dislocation of the patella and of the shoulder: their association with familial joint laxity. J Bone Joint Surg Br. 1960;42-B:721-727.Google Scholar
  7. 7.
    Sutro J. Hypermobility of the knee due to over lengthened capsular and ligamentous tissues. Surgery. 1947;21:67-76.PubMedGoogle Scholar
  8. 8.
    Kirk JA, Ansell BM, Bywaters EG. The hyper mobility syndrome. Musculoskeletal complaints associated with generalized joint hypermobility. Ann Rheum Dis. 1967;26:419-425.PubMedCrossRefGoogle Scholar
  9. 9.
    Wood PH. Is hypermobility a discrete entity? Proc R Soc Med. 1971;64:690-692.PubMedGoogle Scholar
  10. 10.
    Child AH. Joint hypermobility syndrome: inherited disorder of collagen synthesis. J Rheumatol. 1986;13:239-243.PubMedGoogle Scholar
  11. 11.
    Bird HA. Heritable collagen disorders. In: Reports on the Rheumatic Diseases (Series 5): Topical Reviews. Chesterfield: Arthritis Research Campaign; 2005.Google Scholar
  12. 12.
    Ansell BM. Hypermobility of joints. Mod Trends Orthop. 1972;6:419-425.Google Scholar
  13. 13.
    Grahame R. Time to take hypermobility seriously (in adults and children). Rheumatology. 2001;40:485-487.PubMedCrossRefGoogle Scholar
  14. 14.
    Howes RJ, Isdale IC. The loose back: an unrecognised syndrome. Rheumatol Phys Med. 1971;11:72-77.PubMedCrossRefGoogle Scholar
  15. 15.
    Lewkonia RM, Ansell BM. Articular hypermobility simulating chronic rheumatic disease. Arch Dis Child. 1983;58:988-992.PubMedCrossRefGoogle Scholar
  16. 16.
    Gedalia A, Person DA, Brewer EJ, Giannini EH. Hypermobility of the joints in juvenile episodic arthritis/arthralgia. J Pediatr. 1985;107:873-876.PubMedCrossRefGoogle Scholar
  17. 17.
    Adib N, Davies K, Grahame R, Woo P, Murray KJ. Joint hypermobility syndrome in childhood. A not so benign multisystem disorder? Rheumatology. 2005;44:744-750.PubMedCrossRefGoogle Scholar
  18. 18.
    Grahame R, Beighton P. Physical properties of the skin in the Ehlers-Danlos syndrome. Ann Rheum Dis. 1969;28:246-252.PubMedCrossRefGoogle Scholar
  19. 19.
    Grahame R. A method for measuring human skin elasticity in vivo with observations of the effects of age, sex and pregnancy. Clin Sci. 1970;39:223-229.PubMedGoogle Scholar
  20. 20.
    Silverman S, Constine L, Harvey W, Grahame R. Survey of joint mobility and in vivo skin elasticity in London schoolchildren. Ann Rheum Dis. 1975;34:177-180.PubMedCrossRefGoogle Scholar
  21. 21.
    Beighton PH, Price A, Lord J, Dickson E. Variants of the ehlers-danlos syndrome. Clinical, biochemical, haematological, and chromosomal features of 100 patients. Ann Rheum Dis. 1969;28:228-245.PubMedCrossRefGoogle Scholar
  22. 22.
    Bird HA, Tribe CR, Bacon PA. Joint hypermobility leading to osteoarthrosis and chondrocalcinosis. Ann Rheum Dis. 1978;37:203-211.PubMedCrossRefGoogle Scholar
  23. 23.
    Lewkonia RM. Hypermobility of joints. Arch Dis Child. 1987;62:1-2.PubMedCrossRefGoogle Scholar
  24. 24.
    Gurley-Green S. Living with the hypermobility syndrome. Rheumatology. 2001;40:487-489.PubMedCrossRefGoogle Scholar
  25. 25.
    Grahame R, Jenkins JM. Joint hypermobility – asset or liability? a study of joint mobility in ballet dancers. Ann Rheum Dis. 1972;31:109-111.PubMedCrossRefGoogle Scholar
  26. 26.
    Horan FT, Beighton PH. Recessive inheritance of generalized joint hypermobility. Rheumatol Rehabil. 1973;12:47-49.PubMedCrossRefGoogle Scholar
  27. 27.
    Beighton P, Solomon L, Soskolne CL. Articular mobility in an African population. Ann Rheum Dis. 1973;32:413-418.PubMedCrossRefGoogle Scholar
  28. 28.
    Bird HA. Joint hypermobility in children. Rheumatology. 2005;44:703-704.PubMedCrossRefGoogle Scholar
  29. 29.
    Harris H, Joseph J. Variation in extension of the metacarpo-phalangeal and interphalangeal joints of the thumb. J Bone Joint Surg Br. 1949;31-B:547-559.Google Scholar
  30. 30.
    Troup JDG, Hood CA, Chapman AE. Measurement of the sagittal mobility of the lumbar spine and hips. Ann Phys Med. 1968;9:308-321.PubMedGoogle Scholar
  31. 31.
    Barnett CH. The mobility of synovial joints. Rheumatol Phys Med. 1971;11:20-27.PubMedCrossRefGoogle Scholar
  32. 32.
    Fairbank JC, Pynsent PB, Phillips H. Quantitative measurements of joint mobility in adolescents. Ann Rheum Dis. 1984;43:288-294.PubMedCrossRefGoogle Scholar
  33. 33.
    Larsson LG, Baum J, Mudholkar GS. Hypermobility: features and differential incidence between the sexes. Arthritis Rheum. 1987;30:1426-1430.PubMedCrossRefGoogle Scholar
  34. 34.
    Wordsworth P, Ogilvie D, Smith R, Sykes B. Joint mobility with particular reference to racial variation and inherited connective tissue disorders. Br J Rheumatol. 1987;26:9-12.PubMedCrossRefGoogle Scholar
  35. 35.
    Grahame R, Bird H. British consultant rheumatologists’ perceptions about the hypermobility syndrome: a national survey. Rheumatology (Oxford). 2001;40:559-562.CrossRefGoogle Scholar
  36. 36.
    Tinkle BT, Bird HA, Grahame R, Lavallee M, Levy HP, Sillence D. The lack of clinical distinction between the hypermobility type of Ehlers-Danlos syndrome and the joint hypermobility syndrome (a.k.a. hypermobility syndrome). Am J Med Genet A. 2009;149A(11):2368-2370.PubMedCrossRefGoogle Scholar
  37. 37.
    Beighton P et al. International nosology of heritable disorders of connective tissue, Berlin, 1986. Am J Med Genet. 1988;29:581-594.PubMedCrossRefGoogle Scholar
  38. 38.
    Beighton P, De Paepe A, Steinmann B, Tsipouras P, Wenstrup RJ. Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Am J Med Genet. 1998;77:31-37.PubMedCrossRefGoogle Scholar
  39. 39.
    McKusick VA (2009) Mendelian inheritance in man. Catalogs of autosomal dominant, autosomal recessive and Χ-linked phenotype. Online www.ncbi.nlm.nih.gov/omim/.

Copyright information

© Springer-Verlag London Limited 2012

Authors and Affiliations

  • Peter Beighton
    • 1
  • Rodney Grahame
    • 2
  • Howard Bird
    • 3
  1. 1.Department of Human GeneticsUniversity of Cape TownCape TownSouth Africa
  2. 2.Department of RheumatolgyUniversity College HospitalLondonUnited Kingdom
  3. 3.Department of Musculo–Skeletal MedicineUniversity of LeedsLeedsUnited Kingdom

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