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Chemotherapeutic Agents for Urologic Oncology

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Practical Urology: Essential Principles and Practice

Part of the book series: Springer Specialist Surgery Series ((SPECIALIST))

Abstract

The main goal of chemotherapy is to cure cancer by killing the neoplastic cells. To keep the cancer from metastasizing, chemotherapy may be used in combination with other cancer treatments, such as surgery and radiotherapy. In widespread, fast-growing cancers, chemotherapy reduces cellular proliferation, eases symptoms, and improves the quality of life. When it is employed after the primary tumor has been treated by some other modality, it is called adjuvant chemotherapy. Sometimes neoadjuvant chemotherapy is employed, which refers to the initial use of chemotherapy in patients with localized cancer in order to reduce tumor burden, there by rendering local therapy (surgery or radiotherapy) more effective. A common procedure in human cancer therapy is combination chemotherapy that refers to the parallel or sequential use of several different antineoplastic agents in order to enhance their effectiveness. Combining chemotherapy with targeted therapies is an investigational approach under development. This chapter presents a comprehensive overview of the use of chemotherapeutics and targeted agents in the treatment of urologic malignancies.

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Author information

Authors and Affiliations

  1. Department of Urology, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium

    Hendrik Van Poppel

  2. University of Hospital Gasthuisberg, Katholieke Universiteit Leuven, Herestraat 49, B 3000, Leuven, Belgium

    Filip Ameye (Consultant Urologist)

Authors
  1. Hendrik Van Poppel
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  2. Filip Ameye
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Editor information

Editors and Affiliations

  1. Dept. of Urology, J Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, United Kingdom

    Christopher R. Chapple

  2. Dept. Urology, University of Virginia Health System, Charlottesville, Virgin Islands, USA

    William D. Steers

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© 2011 Springer London

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Van Poppel, H., Ameye, F. (2011). Chemotherapeutic Agents for Urologic Oncology. In: Chapple, C., Steers, W. (eds) Practical Urology: Essential Principles and Practice. Springer Specialist Surgery Series. Springer, London. https://doi.org/10.1007/978-1-84882-034-0_13

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  • DOI: https://doi.org/10.1007/978-1-84882-034-0_13

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-033-3

  • Online ISBN: 978-1-84882-034-0

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