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Thyroid Cancer and the Skin

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Thyroid Disorders with Cutaneous Manifestations

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Editorial Perspective

“Doctor, is this lump anything important?” This is a question that dermatologists face on a daily basis. Most frequently, lesions are usually benign cysts, nevi, or adnexal tumors. On occasion, however, they may be cutaneous metastases. Although such lesions usually occur in patients with a known history of malignancy, they may be the initial presentation of a cancer. Thyroid cancers may metastasize to the skin; when routine histology is equivocal, immunohistochemical stains may allow for a precise diagnosis. Although the presentation of cutaneous metastases is associated with advanced disease, the dermatologist, has the unique opportunity to recognize rare syndromes associated with thyroid malignancies before they develop. By diagnosing these entities, notably multiple endocrine neoplasia type 2, the Carney complex, and Cowden syndrome, clinicians may be able to prevent thyroid tumors from developing in these patients and their kin. This chapter details the spectrum of thyroid cancers, their propensity to metastasize, the association with fine-needle aspiration, and the genetic syndromes associated with thyroid tumors.

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Authors and Affiliations

  1. Department of Medicine, Division of Haematology and Medical Oncology, Cooper University Hospital, Voorhees, NJ, USA

    Robert A. Somer MD

  2. Department of Haematology and Medical Oncology, Cooper University Hospital, Camden, NJ, USA

    Nati Lerman MD

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  1. Robert A. Somer MD
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Editors and Affiliations

  1. University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Marlton, NJ, USA

    Warren R. Heymann MD

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Somer, R.A., Lerman, N. (2008). Thyroid Cancer and the Skin. In: Heymann, W.R. (eds) Thyroid Disorders with Cutaneous Manifestations. Springer, London. https://doi.org/10.1007/978-1-84800-187-9_6

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