Pharmacological Treatment of Pulmonary Hypertension

  • Mary P. Mullen
  • David L. Wessel

Elevated pulmonary arterial pressure arises from three well-characterized vascular changes: vasoconstriction, thrombus formation, or proliferation of smooth muscle and/or endothelial cells in the pulmonary vessels. Thus, pulmonary hypertension is associated with conditions causing chronic vasoconstriction, thrombosis, or abnormalities of vessel function.


Nitric Oxide Nitric Oxide Pulmonary Hypertension Congenital Heart Disease Pulmonary Arterial Hypertension 
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© Springer-Verlag London Limited 2008

Authors and Affiliations

  • Mary P. Mullen
    • 1
  • David L. Wessel
    • 1
  1. 1.Department of Cardiac Intensive CareChildren's Hospital BostonBostonUSA

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