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Epidemiology

  • Chapter
Atlas of Psoriatic Arthritis

Abstract

Psoriatic arthritis (PsA) has been defined as an inflammatory arthritis, usually seronegative for rheumatoid factor, associated with psoriasis [1]. Other clinical features associated with PsA include the presence of spondylitis and sacroiliitis, dactylitis (swelling of the whole digit), enthesitis (inflammation at tendon insertion), and extra-articular manifestations of seronegative spondyloarthropathies such as iritis, urethritis, inflammatory bowel changes, and aortic root dilatation. The original description of PsA was that of a mild disease compared with rheumatoid arthritis (RA) [2]. Moll and Wright described five clinical patterns of PsA:

  • predominantly distal joint disease, with distal interphalangeal (DIP) joint involvement;

  • an oligoarthritis, usually asymmetric;

  • a symmetric polyarthritis indistinguishable from RA;

  • arthritis mutilans; and

  • spondyloarthritis.

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  1. University of Toronto School of Medicine, Toronto, Ontario, Canada

    Dafna D. Gladman

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  1. School of Medicine, University of Washington, Seattle, WA, USA

    P. J. Mease MED (RHUUH)

  2. Academic Unit of Musculoskeletal and Rehabilitation Medicine, University of Leeds, Leeds, UK

    P. S. Helliwell DM, PhD, FRCP

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Gladman, D.D. (2008). Epidemiology. In: Mease, P.J., Helliwell, P.S. (eds) Atlas of Psoriatic Arthritis. Springer, London. https://doi.org/10.1007/978-1-84628-897-5_1

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