Acute coronary syndrome (ACS) is a spectrum of clinical events ranging from unstable angina (UA) to acute myocardial infarction (AMI). AMI includes both non-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI). UA and NSTEMI have similar patho-physiologic and clinical presentations. Often they are diffi cult to distinguish on initial appearance and are frequently grouped together as one clinical syndrome. However, NSTEMI portends an increased risk due to an elevation in cardiac biomarkers refl ecting myocardial necrosis. NSTEMI is a highly prevalent and life-threatening manifestation of ACS accounting for more than 1.2 million patient hospitalizations in the United States alone [1] and is a major cause of morbidity and mortality in the Western world.
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Tamis-Holland, J.E., Joshi, S., Palazzo, A., Bangalore, S. (2008). Diagnosis and Treatment of Non-ST-Segment Elevation Myocardial Infarction. In: Hong, M.K., Herzog, E. (eds) Acute Coronary Syndrome. Springer, London. https://doi.org/10.1007/978-1-84628-869-2_7
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