Skip to main content
SpringerLink
Log in

Arrhythmia in Acute Heart Failure

  • Chapter
Acute Heart Failure

  • 2452 Accesses

Abstract

The ubiquity of arrhythmias, both atrial and ventricular, in chronic heart failure (HF) is well established, and their significance and treatment have been studied quite extensively. The prevalence, significance, and treatment of arrhythmias in acutely decompensated heart failure have been less studied.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
EUR 29.95
Price includes VAT (Austria)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
EUR 139.09
Price includes VAT (Austria)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
EUR 181.49
Price includes VAT (Austria)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
EUR 252.99
Price includes VAT (Austria)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Benza R, Tallaj J, Felker G, et al. The impact of arrhythmias in acute heart failure. J Card Fail 2004;10:279–84.

    Article  PubMed  Google Scholar 

  2. Adams K Jr, Fonarow G, Emerman C, et al. Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J 2005;149:209–16.

    Article  PubMed  Google Scholar 

  3. Fonarow G, Abraham W, Albert N, et al. Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZEHF): rationale and design. Am Heart J 2004;148:43–51.

    Article  PubMed  Google Scholar 

  4. Ehrlich J, Nattel S, Hohnloser S. Atrial fibrillation and congestive heart failure: specific considerations at the intersection of two common and important cardiac disease sets. J Cardiovasc Electrophysiol 2002;13:399–405.

    Article  PubMed  Google Scholar 

  5. Francis G. Development of arrhythmias in the patient with congestive heart failure: pathophysiology, prevalence and prognosis. Am J Cardiol 1986;57:3B–7B.

    Article  CAS  PubMed  Google Scholar 

  6. Holmes J, Kubo S, Cody R, et al. Milrinone in congestive heart failure: observations on ambulatory ventricular arrhythmias. Am Heart J 1985;110:800–6.

    Article  CAS  PubMed  Google Scholar 

  7. Meinertz T, Hofmann T, Kasper W, et al. Significance of ventricular arrhythmias in idiopathic dilated cardiomyopathy. Am J Cardiol 1984;53:902–7.

    Article  CAS  PubMed  Google Scholar 

  8. Doval H, Nul D, Grancelli H, et al. Nonsustained ventricular tachycardia in severe heart failure. Independent marker of increased mortality due to sudden death. GESICA-GEMA Investigators. Circulation 1996;94:3198–203.

    CAS  PubMed  Google Scholar 

  9. Singh S, Fisher S, Carson P, et al. Prevalence and significance of nonsustained ventricular tachycardia in patients with premature ventricular contractions and heart failure treated with vasodilator therapy. Department of Veterans Affairs CHF STAT Investigators. J Am Coll Cardiol 1998;32:942–7.

    Article  CAS  PubMed  Google Scholar 

  10. Teerlink J, Jalaluddin M, Anderson S, et al. Ambulatory ventricular arrhythmias in patients with heart failure do not specifically predict an increased risk of sudden death. PROMISE (Prospective Randomized Milrinone Survival Evaluation) Investigators. Circulation 2000;101:40–6.

    CAS  PubMed  Google Scholar 

  11. Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. JAMA 2002;287:1531–40.

    Google Scholar 

  12. Burger A, Horton D, LeJemtel T, et al. Effect of nesiritide (B-type natriuretic peptide) and dobutamine on ventricular arrhythmias in the treatment of patients with acutely decompensated congestive heart failure: the PRECEDENT study. Am Heart J 2002;144:1102–8.

    Article  CAS  PubMed  Google Scholar 

  13. Cleland J, Swedberg K, Follath F, et al. The EuroHeart Failure survey programme-a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis. Eur Heart J 2003;24:442–63.

    Article  CAS  PubMed  Google Scholar 

  14. Follath F, Cleland J, Just H, et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet 2002;360:196–202.

    Article  CAS  PubMed  Google Scholar 

  15. Gattis W, O’connor C, Gallup D, et al. Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure: results of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy in Heart Failure (IMPACT-HF) trial. J Am Coll Cardiol 2004;43:1534–41.

    Article  CAS  PubMed  Google Scholar 

  16. Hasdai D, Topol E, Kilaru R, et al. Frequency, patient characteristics, and outcomes of mild-tomoderate heart failure complicating ST-segment elevation acute myocardial infarction: lessons from 4 international fibrinolytic therapy trials. Am Heart J 2003;145:73–9.

    Article  PubMed  Google Scholar 

  17. Kaluski E, Kobrin I, Zimlichman R, et al. RITZ-5: randomized intravenous TeZosentan (an endothelin-A/B antagonist) for the treatment of pulmonary edema: a prospective, multicenter, double-blind, placebo-controlled study. J Am Coll Cardiol 2003;41:204–10.

    Article  CAS  PubMed  Google Scholar 

  18. O’Connor C, Gattis W, Adams K Jr, et al. Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4). J Am Coll Cardiol 2003;41:1452–7.

    Article  PubMed  Google Scholar 

  19. O’Connor C, Stough W, Gallup DS. Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry. J Card Fail 2005;11:200–5.

    Article  PubMed  Google Scholar 

  20. Rudiger A, Harjola V, Muller A, et al. Acute heart failure: clinical presentation, one-year mortality and prognostic factors. Eur J Heart Fail 2005;7:662–70.

    Article  PubMed  Google Scholar 

  21. Torre-Amione G, Young J, Colucci W et al. Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure. J Am Coll Cardiol 2003;42:140–7.

    Article  CAS  PubMed  Google Scholar 

  22. Zannad F, Briancon S, Juilliere Y, et al. Incidence, clinical and etiologic features, and outcomes of advanced chronic heart failure: the EPICAL Study. Epidemiologie de l’Insuffisance Cardiaque Avancee en Lorraine. J Am Coll Cardiol 1999;33:734–42.

    Article  CAS  PubMed  Google Scholar 

  23. Ravens U. Mechano-electric feedback and arrhythmias. Prog Biophys Mol Biol 2003;82:255–66.

    Article  PubMed  Google Scholar 

  24. Sachs F. Mechanoelectric transduction. In: Zipes D, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. Philadelphia: Saunders; 2004:96–102.

    Google Scholar 

  25. Calaghan S, Belus A, White E. Do stretch-induced changes in intracellular calcium modify the electrical activity of cardiac muscle? Prog Biophys Mol Biol 2002;82:81–95.

    Article  Google Scholar 

  26. Zabel M, Koller B, Sachs F, et al. Stretch-induced voltage changes in the isolated beating heart: importance of the timing of stretch and implications for stretch-activated ion channels. Cardiovasc Res 1996;32:120–30.

    CAS  PubMed  Google Scholar 

  27. Janse M, Coronel R, Wilms-Schopman F, et al. Mechanical effects on arrhythmogenesis: from pipette to patient. Prog Biophys Mol Biol 2003;82:187–95.

    Article  PubMed  Google Scholar 

  28. Chen R, Penny D, Greve G, et al. Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambs. Am J Physiol Heart Circ Physiol 2004;286:H1008–14.

    Article  CAS  PubMed  Google Scholar 

  29. Hansen D, Borganelli M, Stacy GP, Jr, et al. Dosedependent inhibition of stretch-induced arrhythmias by gadolinium in isolated canine ventricles. Evidence for a unique mode of antiarrhythmic action. Circ Res 1991;69:820–31.

    CAS  PubMed  Google Scholar 

  30. Bode F, Sachs F, Franz M. Tarantula peptide inhibits atrial fibrillation. Nature 2001;409:35–6.

    Article  CAS  PubMed  Google Scholar 

  31. Ausma J, Borgers M. Dedifferentiation of atrial cardiomyocytes: from in vivo to in vitro. Cardiovasc Res 2002;55(9–12).

    Google Scholar 

  32. Shi Y, Li D, Tardif J, et al. Enalapril effects on atrial remodeling and atrial fibrillation in experimental congestive heart failure. Cardiovasc Res 2002;54:456–61.

    Article  CAS  PubMed  Google Scholar 

  33. Pogwizd S, Schlotthauer K, Li L, et al. Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res 2001;88:1159–554.

    Article  CAS  PubMed  Google Scholar 

  34. Janse M. Electrophysiological changes in heart failure and their relationship to arrhythmogenesis. Cardiovasc Res 2004;61:208–17.

    Article  CAS  PubMed  Google Scholar 

  35. Nuss H, Kaab S, Kass D, et al. Cellular basis of ventricular arrhythmias and abnormal automaticity in heart failure. Am J Physiol 1999;277:H80–H91.

    CAS  PubMed  Google Scholar 

  36. Vermeulen J, McGuire M, Opthof T, et al. Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts. Cardiovasc Res 1994;28:1547–54.

    Article  CAS  PubMed  Google Scholar 

  37. Aronson D, Burger A. Diabetes and the occurrence of ventricular arrhythmic events in patients with severe left ventricular dysfunction. Diabetologia 2002;45:1440–5.

    Article  CAS  PubMed  Google Scholar 

  38. Aronson D, Burger A. Neurohumoral activation and ventricular arrhythmias in patients with decompensated congestive heart failure: role of endothelin. Pacing Clin Electrophysio 2003;26:703–10.

    Article  Google Scholar 

  39. Amsallem E, Kasparian C, Haddour G, et al. Phosphodiesterase III inhibitors for heart failure. Cochrane Database Syst Rev 2005;CD00:2230.

    Google Scholar 

  40. The effect of digoxin on mortality and morbidity in patients with heart failure. The Digitalis Investigation Group. N Engl J Med 1997;336:525–33.

    Google Scholar 

  41. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999;353:2001–7.

    Google Scholar 

  42. Packer M, Bristow M, Cohn J, et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group. N Engl J Med 1996;334:1349–55.

    Article  CAS  PubMed  Google Scholar 

  43. Brodine W, Tung R, Lee J, et al. Effects of betablockers on implantable cardioverter defibrillator therapy and survival in the patients with ischemic cardiomyopathy (from the Multicenter Automatic Defibrillator Implantation Trial-II). Am J Cardiol 2005;96:691–5.

    Article  CAS  PubMed  Google Scholar 

  44. Aronson D, Burger A. Concomitant beta-blocker therapy is associated with a lower occurrence of ventricular arrhythmias in patients with decompensated heart failure. J Card Fail 2002;8:79–85.

    Article  CAS  PubMed  Google Scholar 

  45. Nieminen M, Bohm M, Cowie M, et al. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Heart Failure of the European Society of Cardiology. Eur Heart J 2005;26:384–416.

    Article  PubMed  Google Scholar 

  46. Mitchell L, Powell J, Gillis A, et al. Are lipid-lowering drugs also antiarrhythmic drugs? An analysis of the Antiarrhythmics versus Implantable Defibrillators (AVID) trial. J Am Coll Cardiol 2003;42:81–7.

    Article  CAS  PubMed  Google Scholar 

  47. Vyas A, Guo H, Moss A et al. Reduction in ventricular tachyarrhythmias with statins in the Multicenter Automatic Defibrillator Implantation Trial (MADIT)-II. J Am Coll Cardiol 2006;47:769–73.

    Article  CAS  PubMed  Google Scholar 

  48. Pitt B, Remme W, Zannad F, et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 2003;348:1309–21.

    Article  CAS  PubMed  Google Scholar 

  49. Pitt B, Zannad F, Remme W, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999;341:709–17.

    Article  CAS  PubMed  Google Scholar 

  50. Ramires F, Mansur A, Coelho O, et al. Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. Am J Cardiol 2000;85:1207–11.

    Article  CAS  PubMed  Google Scholar 

  51. Callans DJ, Josephson ME. Ventricular tachycardia in patients with coronary artery disease. In: Zipes D, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. Philadelphia: Saunders; 2004:569–74.

    Google Scholar 

  52. Fuster V, Ryden L, Cannom D, et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation—executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation). J Am Coll Cardiol 2006;48:854–906.

    Article  PubMed  Google Scholar 

  53. Joglar J, Hamdan M, Ramaswamy K, et al. Initial energy for elective external cardioversion of persistent atrial fibrillation. Am J Cardiol 2000;86:348–50.

    Article  CAS  PubMed  Google Scholar 

  54. Wozakowska-Kaplon B, Janion M, Sielski J, et al. Efficacy of biphasic shock for transthoracic cardioversion of persistent atrial fibrillation: can we predict energy requirements? Pacing Clin Electrophysiol 2004;27:764–8.

    Article  PubMed  Google Scholar 

  55. Chicos A, Mykytsey A, Lavi N, Avitall B. Atrial remodeling in an atrial fibrillation model without left ventricular systolic dysfunction. Heart Rhythm 2006;3(1S):S306.

    Article  Google Scholar 

  56. Zipes D, Camm A, Borggrefe M, et al. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death). J Am Coll Cardiol 2006;48:e247–346.

    Article  PubMed  Google Scholar 

  57. Cleland J, Ghosh J, Freemantle N, et al. Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-Lipids and cardiac resynchronisation therapy in heart failure. Eur J Heart Fail 2004;6:501–8.

    Article  PubMed  Google Scholar 

  58. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 2005;112:IV1–203.

    Google Scholar 

  59. Harding J, Piacentino V III, Rothman S, et al. Prolonged repolarization after ventricular assist device support is associated with arrhythmias in humans with congestive heart failure. J Card Fail 2005;11:227–32.

    Article  PubMed  Google Scholar 

  60. Ziv O, Dizon J, Thosani A, et al. Effects of left ventricular assist device therapy on ventricular arrhythmias. J Am Coll Cardiol 2005;45:1428–34.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cardiology, Northwestern University, Chicago, IL, USA

    Alexandru B. Chicos MD & Alan H. Kadish MD

Authors
  1. Alexandru B. Chicos MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alan H. Kadish MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Anesthesiology and Critical Care Medicine, Lariboisière University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France

    Alexandre Mebazaa MD, PhD (Professor of Medicine) (Professor of Medicine)

  2. Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

    Mihai Gheorghiade MD, FACC (Professor of Medicine and Surgery, Associate Chief, Division of Cardiology and Chief, Cardiology Clinical Service) (Professor of Medicine and Surgery, Associate Chief, Division of Cardiology and Chief, Cardiology Clinical Service)

  3. Department of Cardiology Centre d’Investigation Clinique (CIC), INSERM U-684, Centre Hospitalier Universitaire, University Henri Poincaré, Nancy, France

    Faiez M. Zannad MD, PhD, FESC (Professor of Medicine) (Professor of Medicine)

  4. Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Camden, NJ, USA

    Joseph E. Parrillo MD (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director) (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director)

  5. Cooper Heart Institute, Cooper University Hospital, Camden, NJ, USA

    Joseph E. Parrillo MD (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director) (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director)

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag London Limited

About this chapter

Cite this chapter

Chicos, A.B., Kadish, A.H. (2008). Arrhythmia in Acute Heart Failure. In: Mebazaa, A., Gheorghiade, M., Zannad, F.M., Parrillo, J.E. (eds) Acute Heart Failure. Springer, London. https://doi.org/10.1007/978-1-84628-782-4_21

Download citation

  • DOI: https://doi.org/10.1007/978-1-84628-782-4_21

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-781-7

  • Online ISBN: 978-1-84628-782-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation