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Urological Oncology pp 179–193Cite as

Clinical Trials and Their Principles

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Abstract

Clinical trials are needed for the development and evaluation of any type of treatment used to detect, prevent, or treat genitourinary cancer. This chapter introduces clinical trials in this context. The discussion largely focuses on the design and implementation of a clinical trial in its various stages. Possible sources of bias in clinical trials and methods of minimizing or eliminating this bias are also discussed.

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Author information

Authors and Affiliations

  1. Department of Quantitative Health Sciences Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH, USA

    Denise C. Babineau PhD & Michael W. Kattan PhD

Authors
  1. Denise C. Babineau PhD
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  2. Michael W. Kattan PhD
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Editor information

Editors and Affiliations

  1. St. Bartholomew’s and Homerton Hospitals Queen Mary Barts and the London School of Medicine and Dentistry, University of London, London, UK

    Vinod H. Nargund PhD, FRCS (Urol), FEBU (Chair, Uro-Oncology MDT and Consultant Urological Surgeon) (Chair, Uro-Oncology MDT and Consultant Urological Surgeon)

  2. Cleveland Clinic Taussig Cancer Center, Cleveland, OH, USA

    Derek Raghavan MD, PhD, FACP, FRACP (Chairman and Director) (Chairman and Director)

  3. Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA

    Howard M. Sandler MD (Professor and Senior Associate Chair) (Professor and Senior Associate Chair)

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© 2008 Springer-Verlag London Limited

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Babineau, D.C., Kattan, M.W. (2008). Clinical Trials and Their Principles. In: Nargund, V.H., Raghavan, D., Sandler, H.M. (eds) Urological Oncology. Springer, London. https://doi.org/10.1007/978-1-84628-738-1_8

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  • DOI: https://doi.org/10.1007/978-1-84628-738-1_8

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-387-1

  • Online ISBN: 978-1-84628-738-1

  • eBook Packages: MedicineMedicine (R0)

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