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Renal Failure, Dialysis, and Transplantation: Management of Tumors in Solitary Kidney and Bilateral Renal Tumors

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Urological Oncology

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Abstract

This chapter discusses the renal problems encountered in the management of adult genitourinary cancers. Maintenance of renal function is crucial in the management of most malignancies including genitourinary cancer, as optimal renal function is necessary for multimodal cancer therapy. There are a number of scenarios in which renal function is likely to be compromised as a result of either the cancer itself or the treatment:

  1. 1.

    Obstructive uropathy, which can be bilateral or unilateral, supravesical (above the vesicoureteric junction) or infravesical (below the vesicoureteric junction) (Table 12.1)

  2. 2.

    Renal cell carcinoma in solitary kidney

  3. 3.

    Preexisting renal disease in a patient with cancer

  4. 4.

    Nephrotoxicity induced by high-dose chemotherapy

  5. 5.

    Malignancies in renal transplant patients

  6. 6.

    Effects of previous cancer treatment: radiotherapy, chemotherapy

  7. 7.

    Renal damage as a result of nephrotoxicity due to analgesics and antibiotics

  8. 8.

    Paraneoplastic syndromes

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Authors and Affiliations

  1. Department of Renal Medicine and Transplantation, Bart’s and the London National Health Service Trust, London, UK

    Raj C. Thuraisingham MRCP

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  1. Raj C. Thuraisingham MRCP
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Editors and Affiliations

  1. St. Bartholomew’s and Homerton Hospitals Queen Mary Barts and the London School of Medicine and Dentistry, University of London, London, UK

    Vinod H. Nargund PhD, FRCS (Urol), FEBU (Chair, Uro-Oncology MDT and Consultant Urological Surgeon) (Chair, Uro-Oncology MDT and Consultant Urological Surgeon)

  2. Cleveland Clinic Taussig Cancer Center, Cleveland, OH, USA

    Derek Raghavan MD, PhD, FACP, FRACP (Chairman and Director) (Chairman and Director)

  3. Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA

    Howard M. Sandler MD (Professor and Senior Associate Chair) (Professor and Senior Associate Chair)

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Thuraisingham, R.C. (2008). Renal Failure, Dialysis, and Transplantation: Management of Tumors in Solitary Kidney and Bilateral Renal Tumors. In: Nargund, V.H., Raghavan, D., Sandler, H.M. (eds) Urological Oncology. Springer, London. https://doi.org/10.1007/978-1-84628-738-1_12

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  • DOI: https://doi.org/10.1007/978-1-84628-738-1_12

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-387-1

  • Online ISBN: 978-1-84628-738-1

  • eBook Packages: MedicineMedicine (R0)

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