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The Nervous System

  • Chirukandath Gopinath
  • Vasanthi Mowat
Chapter

Abstract

The importance of correct and adequate sampling of central nervous system in laboratory animals is stressed. Lesions pertaining to neurons such as necrosis, loss, and vacuolation are illustrated. Neuronal changes affecting the cerebrum and cerebellum are included. Distal and proximal axonopathies with examples are described with representative figures. Other changes discussed include demyelination, myelin oedema, and inflammatory lesions in different laboratory animals. Changes occurring in glial cells and choroid plexus are also described. A brief section on induced gliomas in rats is also included.

Keywords

Dorsal Root Ganglion Glial Fibrillary Acidic Protein Carbon Disulphide Myelin Damage Distal Axonopathies 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Chirukandath Gopinath
    • 1
  • Vasanthi Mowat
    • 2
  1. 1.Consultant in Toxicology and PathologyCambridgeshireUK
  2. 2.Huntingdon Life SciencesCambridgeshireUK

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