Key Points
-
The relationship between menopause and skeletal health
-
The animal model of menopause and its use in research
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The background of maslinic acid (including sources of maslinic acid), and pharmacological research into maslinic acid
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The effects of maslinic acid on the ovariectomy mouse model
-
Maslinic acid’s potential toxicity in animal model
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Abbreviations
- BMD:
-
Bone mineral density
- BMM:
-
Bone marrow macrophage
- RANKL:
-
Receptor activator of nuclear factor kappa B ligand
- RANK:
-
Receptor activator of nuclear factor kappa B
- OPG:
-
Osteoprotegerin
- IL:
-
Interleukin
- GM-CSF:
-
Granulocyte-macrophage colony-stimulating factor
- M-CSF:
-
Macrophage colony-stimulating factor
- PGE2 :
-
Prostaglandin-E2
- TNFa:
-
Tumor necrosis factor a
- TGFb:
-
Transforming growth factor b
- VCD:
-
4-Vinylcyclohexene diepoxide
- GnRH:
-
Gonadotropin-releasing hormone
- LH:
-
Luteinizing hormone
- FSH:
-
Follicle-stimulating hormone
- HIV:
-
Human immunodeficiency virus
- AIDS:
-
Acquired immunodeficiency syndrome
- WHO:
-
World Health Organization
- GLT-1:
-
Glial glutamate transporter
- NF-kB:
-
Nuclear factor-kappa B
- MAPK:
-
Mitogen-activated protein kinase
- GP:
-
Glycogen phosphorylase
- SHR:
-
Spontaneously hypertensive rats
- MMP:
-
Matrix metallopeptidase
- CTR:
-
Calcitonin receptor
- OVX:
-
Ovariectomy
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Luo, J., Liu, M. (2013). Dietary Plant Maslinic Acid in Ovariectomy Model of Menopause. In: Hollins Martin, C., Watson, R., Preedy, V. (eds) Nutrition and Diet in Menopause. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-373-2_33
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