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Ureteroscopy pp 399–405Cite as

Medical Comorbidities: Anticoagulation and Obesity

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Part of the book series: Current Clinical Urology ((CCU))

Abstract

Retrograde ureterorenoscopy (URS) is a standard treatment approach for renal and ureteral stones, as well as for other upper tract pathology like ureteral stricture disease and transitional cell carcinoma. Obese patients present unique challenges for treatment of stone disease in particular, as shock wave lithotripsy (SWL) has a higher risk of failure in these patients, and percutaneous nephrolithotomy (PNL) may present technical challenges based on large body habitus. URS, then, may be the preferred approach in patients with significant obesity, though there may be anesthesia and surgical challenges to this procedure as well. URS may also be the treatment of choice in patients with bleeding disorders, or those who are anticoagulated, based on bleeding risks associated with alternative modalities (e.g., SWL and PNL). Refinements in ureteroscope and laser technology have enabled safe therapeutic interventions in this population despite their propensity for bleeding. Care to minimize trauma to the upper tract during these interventions is necessary to ensure treatment safety and efficacy.

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References

  1. Wang AJ, Preminger GM. Modern applications of ureteroscopy for intrarenal stone disease. Curr Opin Urol. 2011;21(2):141–4.

    Article  CAS  PubMed  Google Scholar 

  2. Bader MJ, Sroka R, Gratzke C, et al. Laser therapy for upper urinary tract transitional cell carcinoma: indications and management. Eur Urol. 2009;56(1):65–71.

    Article  PubMed  Google Scholar 

  3. Patel RC, Newman RC. Ureteroscopic management of ureteral and ureteroenteral strictures. Urol Clin North Am. 2004;31(3):107–13.

    Article  PubMed  Google Scholar 

  4. Ogden CL, Yanovski SZ, Carroll MD, et al. The epidemiology of obesity. Gastroenterology. 2007;132:2087–102.

    Article  PubMed  Google Scholar 

  5. Duffey BG, Pedro RN, Kriedberg C, et al. Lithogenic risk factors in the morbidly obese population. J Urol. 2008;179:1401–6.

    Article  CAS  PubMed  Google Scholar 

  6. Delakas D, Karyotis I, Daskalopoulos G, et al. Independent predictors of failure of shockwave lithotripsy for ureteral stones employing a second-generation lithotripter. J Endourol. 2003;17(4):201–5.

    Article  PubMed  Google Scholar 

  7. El-Nahas AR, El-Assmy AM, Mansour O, et al. A prospective multivariate analysis of factors predicting stone disintegration by extracorporeal shock wave lithotripsy: the value of high-resolution noncontrast computed tomography. Eur Urol. 2007;51(6):1888–93.

    Article  Google Scholar 

  8. Pearle MS, Nakada SY, Womack S, et al. Outcomes of contemporary percutaneous nephrostolithotomy in morbidly obese patients. J Urol. 1998;160:669–73.

    Article  CAS  PubMed  Google Scholar 

  9. Faerber GJ, Goh M. Percutaneous nephrolithotripsy in the morbidly obese patient. Tech Urol. 1997;3:89–95.

    CAS  PubMed  Google Scholar 

  10. Manohar T, Jain P, Desai M. Supine percutaneous nephrolithotomy: effective approach to high-risk and morbidly obese patients. J Endourol. 2007;21(1):44–9.

    Article  CAS  PubMed  Google Scholar 

  11. Kerbl K, Clayman RV, Chandhoke PS, et al. Percutaneous stone removal with the patient in a flank position. J Urol. 1994;151(3):686–8.

    CAS  PubMed  Google Scholar 

  12. Kanaroglou A, Razvi H. Percutaneous nephrolithotomy under conscious sedation in morbidly obese patients. Can J Urol. 2006;13(3):3153–5.

    PubMed  Google Scholar 

  13. El-Assmy AM, Shokeir AA, El-Nahas AR, et al. Outcome of percutaneous nephrolithotomy: effect of body mass index. Eur Urol. 2007;52:199–204.

    Article  PubMed  Google Scholar 

  14. Tomaszewski JJ, Smaldone MC, Schuster T, et al. Outcomes of percutaneous nephrolithotomy stratified by body mass index. J Endourol. 2010;24(4):547–50.

    Article  PubMed  Google Scholar 

  15. Koo BC, Burtt G, Burgess NA. Percutaneous stone surgery in the obese: outcome stratified according to body mass index. BJU Intl. 2004;93:1296–9.

    Article  CAS  Google Scholar 

  16. Bagrodia A, Gupta A, Raman JD, et al. Impact of body mass index on cost and clinical outcomes after percutaneous nephrostolithotomy. Urology. 2008;72:756–60.

    Article  PubMed  Google Scholar 

  17. Sergeyev I, Koi PT, Jacobs SL, et al. Outcome of percutaneous surgery stratified according to body mass index and kidney stone size. Surg Laparosc Endosc Percutan Tech. 2007;17(3):179–83.

    Article  PubMed  Google Scholar 

  18. Turney BW, Reynard JM, Noble JG, et al. Trends in urological stone disease. BJU Int. 2012;109(7):1082–7.

    Article  PubMed  Google Scholar 

  19. Patel T, Kozakowski K, Hruby G, et al. Skin to stone distance is an independent predictor of stone-free status following shockwave lithotripsy. J Endourol. 2009;23(9):1383–5.

    Article  PubMed  Google Scholar 

  20. Andreoni C, Afane J, Olweny E, et al. Flexible ureteroscopic lithotripsy: first-line therapy for proximal ureteral and renal calculi in the morbidly obese and superobese patient. J Endourol. 2001;15(5):493–8.

    Article  CAS  PubMed  Google Scholar 

  21. Fabrizio MD, Behari A, Bagley DH. Ureteroscopic management of intrarenal calculi. J Urol. 1998;159:1139–43.

    Article  CAS  PubMed  Google Scholar 

  22. Ricchiuti DJ, Smaldone MC, Jacobs BL, et al. Staged retrograde endoscopic lithotripsy as alternative to PCNL in select patients with large renal calculi. J Endourol. 2007;21(12):1421–4.

    Article  PubMed  Google Scholar 

  23. Hyams ES, Munver R, Bird VG, et al. Flexible ureterorenoscopy and Holmium laser lithotripsy for the management of renal stone burdens that measure 2 to 3 cm: a multi-institutional experience. J Endourol. 2010;24(10):1583–8.

    Article  PubMed  Google Scholar 

  24. Grasso M, Conlin M, Bagley D. Retrograde ureteropyeloscopic treatment of 2 cm or greater upper urinary tract and minor staghorn calculi. J Urol. 1998;160:346–51.

    Article  CAS  PubMed  Google Scholar 

  25. Natalin R, Xavier K, Okeke Z, et al. Impact of obesity on ureteroscopic laser lithotripsy of urinary tract calculi. Int Braz J Urol. 2009;35(1):36–42.

    Article  PubMed  Google Scholar 

  26. Bultitude MF, Tiptaft RC, Dasgupta P, et al. Treatment of urolithiasis in the morbidly obese. Obes Surg. 2004;14(3):300–3004.

    Article  PubMed  Google Scholar 

  27. Nguyen TA, Belis JA. Endoscopic management of urolithiasis in the morbidly obese patient. J Endourol. 1998;12(1):30–5.

    Article  Google Scholar 

  28. Best SL, Nakada SY. Flexible ureteroscopy is effective for proximal ureteral stones in both obese and nonobese patients: a two-year, single surgeon experience. Urology. 2011;77:36–9.

    Article  PubMed  Google Scholar 

  29. Dash A, Schuster TG, Hollenbeck BK, et al. Ureteroscopic treatment of renal calculi in morbidly obese patients: a stone-matched comparison. Urology. 2002;60:393–7.

    Article  PubMed  Google Scholar 

  30. Chung SY, Chon CH, Ng CS, et al. Simultaneous bilateral retrograde intrarenal surgery for stone disease in patients with significant comorbidities. J Endourol. 2006;20(10):761–5.

    Article  PubMed  Google Scholar 

  31. Flancbaum L, Choban PSA. Surgical implications of obesity. Annu Rev Med. 1998;49:215–34.

    Article  CAS  PubMed  Google Scholar 

  32. Pliskin MJ, Wikert GA, Dresner ML. Hemorrhagic complications of extracorporeal shock wave lithotripsy in an anticoagulated patient. J Endourol. 1989;3:405–9.

    Article  Google Scholar 

  33. Ruiz H, Saltzman B. Aspirin-induced bilateral renal hemorrhage, after extracorporeal shock wave lithotripsy therapy: implicatiosn and conclusions. J Urol. 1990;143:791–2.

    CAS  PubMed  Google Scholar 

  34. Klingler HC, Kramer G, Lodde M, et al. Stone treatment and coagulopathy. Eur Urol. 2003;43:5–9.

    Google Scholar 

  35. Kuo RL, Aslan P, Fitzgerald KB, et al. Use of ureteroscopy and Holmium:YAG laser in patients with bleeding diatheses. Urology. 1998;52:609–13.

    Article  CAS  PubMed  Google Scholar 

  36. Turna B, Stein RJ, Smaldone MC, et al. Safety and efficacy of flexible ureterorenoscopy and Holmium:YAG lithotripsy for intrarenal stones in anticoagulated cases. J Urol. 2008;179:1415–9.

    Article  PubMed  Google Scholar 

  37. Watterson JD, Girvan AR, Cook AJ, et al. Safety and efficacy of Holmium:YAG laser lithotripsy in patients with bleeding diatheses. J Urol. 2002;168:442–5.

    Article  PubMed  Google Scholar 

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Correspondence to Elias S. Hyams M.D. .

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Hyams, E.S., Matlaga, B.R. (2013). Medical Comorbidities: Anticoagulation and Obesity. In: Monga, M. (eds) Ureteroscopy. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-206-3_35

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  • DOI: https://doi.org/10.1007/978-1-62703-206-3_35

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-205-6

  • Online ISBN: 978-1-62703-206-3

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