Advertisement

Taurine (2-Aminoethanesulfonic Acid): Useful in Skin Diseases

Chapter
First Online:
  • 2.4k Downloads
Part of the Nutrition and Health book series (NH)

Abstract

Taurine or 2-aminoethanesulfonic acid occurs naturally in food, especially in seafood and meat. Taurine is used in topical anti-acne therapy. It was used to explore anti-tumor promoting activity in a skin carcinogenesis. It is used in skin ulcers. Due to its antioxidant and anti-apoptotic properties it exerts an antiwrinkle effect on the skin. Taurine (0.05–0.15 g/day) is effective in treating the underlying causes of psoriasis. It is also used in atopic eczema.

Keywords

Taurine Skin cancer Psoriasis Atopic eczema 
This is a preview of subscription content, log in to check access.

References

  1. 1.
    Kendler BS. Taurine: an overview of its role in preventative medicine. Prev Med. 1989;18:79–100.PubMedCrossRefGoogle Scholar
  2. 2.
    Stapleton PP, O’Flaherty L, Redmond HP, Bouchier-Hayes DJ. Host defense—a role for the amino acid taurine. J Parenter Enteral Nutr. 1998;22:42–8.CrossRefGoogle Scholar
  3. 3.
    Lourenço R, Camilo ME. Taurine: a conditionally essential amino acid in humans? An overview in health and disease. Nutr Hosp. 2002;17:262–70.PubMedGoogle Scholar
  4. 4.
    James WD. Clinical practice. Acne. N Engl J Med. 2005;352:1463–72.PubMedCrossRefGoogle Scholar
  5. 5.
    Marcinkiewicz J, Wojas-Pelc A, Walczewska M. Topical taurine bromamine, a new candidate in the treatment of moderate inflammatory acne vulgaris: a pilot study. Eur J Dermatol. 2008;18:433–9.PubMedGoogle Scholar
  6. 6.
    Sun BS, Wang JH, Liu LL, Gong SL, Redmond HP. Taurolidine induces apoptosis of murine melanoma cells in vitro and in vivo by modulation of the Bcl-2 family proteins. J Surg Oncol. 2007;96:241–8.PubMedCrossRefGoogle Scholar
  7. 7.
    Yu JS, Kim AK. Effect of combination of taurine and azelaic acid on antimelanogenesis in murine melanoma cells. J Biomed Sci. 2010;17:S45.PubMedCrossRefGoogle Scholar
  8. 8.
    Nguyen DT, Orgill DP, Murphy GF. The pathophysiologic basis for wound healing and cutaneous regeneration. In: Orgill DP, Blanco C, editors. Biomaterials for treating skin loss. Cambridge: Woodhead Publishing; 2009. p. 25–57.CrossRefGoogle Scholar
  9. 9.
    Tian X, Zhang Z, Wang S, Diao Y, Zhao Z, Lv D. Copper-taurine (CT): a potential organic compound to facilitate infected wound healing. Med Hypotheses. 2009;73:1048–50.PubMedCrossRefGoogle Scholar
  10. 10.
    Gottardi W, Nagl M. N-chlorotaurine, a natural antiseptic with outstanding tolerability. J Antimicrob Chemother. 2010;65:399–409.PubMedCrossRefGoogle Scholar
  11. 11.
    Nagl M, Nguyen V, Gottardi W. Tolerability and efficacy of N-chlorotaurine compared to chloramine T for treatment of chronic leg ulcers with purulent coating. Br J Dermatol. 2003;149:590–7.PubMedCrossRefGoogle Scholar
  12. 12.
    Korponyai C, Kovács R, Erös G, Dikstein S, Kemény L. Antiirritant properties of polyols and amino acids. Dermatitis. 2011;22:141–6.PubMedGoogle Scholar
  13. 13.
    Rona C, Vailati F, Berardesca E. The cosmetic treatment of wrinkles. J Cosmet Dermatol. 2004;3:26–34.PubMedCrossRefGoogle Scholar
  14. 14.
    Janeke G, Siefken W, Carstensen S, Springmann G, Bleck O, Steinhart H, Hoger P, Wittern K, Wenck H, Stab F, Sauermann G, Schreiner V, Doering T. Role of taurine accumulation in keratinocyte hydration. J Invest Dermatol. 2003;121:354–61.PubMedCrossRefGoogle Scholar
  15. 15.
    Stapleton PP, Molloy AM, Rogers S, Bloomfield FJ. Neutrophil taurine in psoriasis. Ir J Med Sci. 1996;165:173–6.PubMedCrossRefGoogle Scholar
  16. 16.
    Herdies C, Weis C. Method of treatment of acne, rosacea and ulcers with tauroidine and/or taurultam in a pharmaceutical composition. Patent No. US 2005/0008684 A1. 2005; p. 3–4.Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of PharmacologyPE Society’s Modern College of PharmacyNigadi, PuneIndia

Personalised recommendations

Cite chapter

Buy options