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Withania somnifera: Use for Skin Disease

  • Anand A. Zanwar
  • Sachin L. Badole
  • Rashmi Saini
Chapter
Part of the Nutrition and Health book series (NH)

Abstract

Withania somnifera (W. somnifera) is popularly known as Ashwagandha. It is a herbal drug from the Indian system of medicine. W. somnifera is an official drug mentioned in the Indian Pharmacopoeia. Of all parts of this plant, the root has been considered to be the most active for therapeutic purposes. The major pharmacological activity of the plant is attributed to the presence of several alkaloids and withaniols. Roots are prescribed in medicines for hiccup, several female disorders, bronchitis, rheumatism, dropsy, stomach and lung inflammations and skin diseases. W. somnifera was found to be effective in prevention of skin carcinoma in UV B radiation-exposed animals, DMBA-induced carcinogenesis and in long-term tumorigenesis. A toxicological study showed that W. somnifera is nontoxic in a wide range of reasonable doses.

Keywords

Ashwagandha Carcinogenesis Withania somnifera Skin cancer 

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Anand A. Zanwar
    • 1
  • Sachin L. Badole
    • 2
  • Rashmi Saini
    • 3
  1. 1.Interactive Research School for Health AffairsBharati Vidyapeeth UniversityDhankawadi, PuneIndia
  2. 2.Department of PharmacologyPE Society’s Modern College of PharmacyNigadi, PuneIndia
  3. 3.Molecular Biology Laboratory, Center of Hematology and Hemotherapy-HEMOCENTROUniversity of Campinas (UNICAMP)CampinasBrazil

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