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Clinical Benefits of Cocoa: An Overview

  • Margarida CastellEmail author
  • Francisco Jose Pérez-Cano
  • Jean-François Bisson
Chapter
Part of the Nutrition and Health book series (NH, volume 7)

Key Points

  • Cocoa intake enhances antioxidant defenses quickly and over a short period after ingestion.

  • Epidemiological studies indicate that cocoa has a cardioprotective effect by improving endothelial function and decreasing platelet aggregation and blood pressure.

  • Clinical evidence suggests that cocoa can be a new and interesting food for regulating mood and brain disorders.

  • Cocoa flavonoids have in vitro anti-inflammatory effects, and preclinical studies show this potential. The immunomodulatory power of cocoa, demonstrated preclinically, may be beneficial in reducing certain states of autoimmunity and hypersensitivity.

  • Although in vitro studies have shown that cocoa flavonoids exert antitumoral effects, further studies are needed.

Keywords

Cocoa Flavonoids Antioxidant Cardiovascular diseases Nervous system Immune system Cancer 

Notes

Acknowledgments

This study was supported by the Ministerio de Ciencia y Tecnología (AGL2005-02823 and AGL2008-02790) and the Generalitat de Catalunya (SGR2009118).

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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Margarida Castell
    • 1
    Email author
  • Francisco Jose Pérez-Cano
    • 1
  • Jean-François Bisson
    • 2
  1. 1.Departament de Fisiologia, Facultat de FarmàciaUniversitat de BarcelonaBarcelonaSpain
  2. 2.Department of Cancerology, Human Pathologies & ToxicologyCentre de Recherche ETAPVandœuvre-lès-NancyFrance

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