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Placental Site Trophoblastic Tumor

Chapter
Part of the Current Clinical Pathology book series (CCPATH)

Abstract

Placental site trophoblastic tumor or PSTT is a bona fide neoplastic proliferation of cells with cytological features of the intermediate trophoblast present at the implantation site. The recognition of the tumor was in late 1970s to early 1980s, although similar lesions had been documented in the literature for over a century ago. The earliest possible description of the lesion was by Marchand in 1895 as “atypical chorioepithelioma” (Monatsschr Geburtshilfe Gynaekol 1:419–38, 1895). Other names of the tumor were used including “atypical choriocarcinoma”, “syncytioma”, a term introduced by Ewing (Am J Obstet Gynecol 56(3):584–6, 1948; Am J Obstet Gynecol 63(4):888–92, 1952; J Philipp Med Assoc 39:720–4, 1963; Surg Gynecol Obstet 10:366–932, 1920), and “chorioepitheliosis” (Gynecol Prat 5(1):31–40, 1954; Z Geburtshilfe Gynakol 147(2):145–203, 1956; Rev Chil Obstet Ginecol 31(4):200–9, 1966). The tumor could be mistaken traditionally as poorly differentiated carcinoma or even sarcoma.

Keywords

PSTT Diagnostic features Differential diagnosis 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of PathologyYale University School of MedicineNew HavenUSA

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