Gestational Trophoblastic Disease: General Aspects

Part of the Current Clinical Pathology book series (CCPATH)


As a major defining characteristic of eutherian mammals, the placenta is a transient organ of female reproduction that nourishes the developing fetus through nutrient supply, waste elimination, and gas exchange. In both Latin and Greek, the placenta means flat cake, in reference to its flat and round appearance in human. The placenta arises from the same fertilized egg that forms the fetus and is essentially a fetomaternal organ consisting of two components: the fetal part (chorion frondosum) and the maternal part (decidua basalis). It has been speculated that ancestral mammals might have evolved to attain the placenta, along with newly acquired retrotransposon-derived genes, or expression of endogenous versions of the genes present in oviparous animals.


Historical review Epidemiology Classification 


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© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of PathologyYale University School of MedicineNew HavenUSA

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