Suicide Risk in Parkinson’s Disease
Suicide is a major but possibly preventable public health issue. In Parkinson’s disease, the rate of completed suicides is the same as or lower than the general population despite the high comorbid risk factors. Suicide ideation and attempts appear to be more common. Depression is identified as the most common factor associated with suicidal behaviours. Following deep brain stimulation surgery targeting the subthalamic nucleus, the rate of completed suicides increases (Standardized Mortality Ratio 12.63–15.64) in the first postoperative year and remains elevated to the fourth postoperative year. Again depression is the single factor most commonly associated with suicidal behaviours in the postoperative state. Suicidal behaviours in PD demonstrate a clear association with depression, thus highlighting the need to screen for and treat depressive symptoms along with actively screening for suicidal ideation in depressed patients.
KeywordsSuicidal Ideation Suicide Attempt Deep Brain Stimulation Suicidal Behaviour Dopaminergic Medication