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Sleep Disordered Breathing in Children pp 263–278Cite as

Apnea of Prematurity

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Part of the book series: Respiratory Medicine ((RM))

Abstract

Almost every extremely low gestational age neonate (ELGAN) is affected by apnea of prematurity (AOP). Yet its precise pathophysiology is incompletely understood. In this chapter, data from observational studies will be reviewed in an attempt better to understand the mechanisms involved in the pathophysiology of AOP, focusing on bradycardia and hypoxemia because they, and not apnea duration, are relevant to the well-being of an infant. Based on these data, this chapter will review the current knowledge on the prevention and treatment—including prone positioning, continuous positive airway pressure (CPAP), nasal intermittent positive pressure ventilation (N-IPPV), and caffeine—of AOP.

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Authors and Affiliations

  1. Department of Neonatology, Tuebingen University Hospital, Calwerstr. 7, Tuebingen, 72076, Germany

    Christian F. Poets MD

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  1. Christian F. Poets MD
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Editors and Affiliations

  1. Section of Sleep Medicine, Pritzker School of Medicine, Department of Pediatrics, S. Maryland Ave. 5721, Chicago, 60637, Illinois, USA

    Leila Kheirandish-Gozal

  2. Pritzker School of Medicine, Comer Children's Hospital, Department of Pediatrics, S. Maryland Ave. 5721, Chicago, 60637, Illinois, USA

    David Gozal

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Poets, C.F. (2012). Apnea of Prematurity. In: Kheirandish-Gozal, L., Gozal, D. (eds) Sleep Disordered Breathing in Children. Respiratory Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-725-9_19

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  • DOI: https://doi.org/10.1007/978-1-60761-725-9_19

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  • Publisher Name: Humana Press, Totowa, NJ

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  • Online ISBN: 978-1-60761-725-9

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