Advertisement

Epidemiological Evidence: IgE, Atopy, and Solid Tumors

  • Michelle C. TurnerEmail author
Chapter

Abstract

Epidemiological investigation into a potential relation between a history of allergic disorders, typically characterized by high levels of IgE, and cancer occurrence has been conducted for at least the past five decades. Recently, there is renewed interest in the field, and the literature is expanding rapidly. This chapter summarizes the epidemiological literature examining the potential relation between allergy and cancer, with a particular focus on the most recent contributions to the field. Although the majority of new and previously published studies evaluated self-reported history of specific allergic disorders (asthma, hay fever, eczema), there were also several new studies examining total or allergen-specific IgE antibodies, hospital discharges for allergic conditions, skin prick tested patients, and allergy-related gene polymorphisms in relation to cancer risk. Although there are a number of inverse relations reported, particularly with pancreatic cancer and glioma, there remain a number of methodological considerations. Further research is recommended in order to better understand the nature of a possible inverse relation and possible mechanisms of action with implications for cancer treatment and prevention. Multidisciplinary collaborations between the population and laboratory-based sciences would be particularly useful.

Keywords

Atopic Dermatitis Standardize Incidence Ratio Acoustic Neuroma Allergic Disorder Significant Inverse Association 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

Michelle C. Turner holds a Canada Graduate Scholarship from the Canadian Institutes of Health Research.

References

  1. 1.
    Turner MC, Chen Y, Krewski D, Ghadirian P (2006) An overview of the association between allergy and cancer. Int J Cancer 118:3124–3132PubMedGoogle Scholar
  2. 2.
    Galli SJ, Tsai M, Piliponsky AM (2008) The development of allergic inflammation. Nature 454:445–454PubMedGoogle Scholar
  3. 3.
    Struck R, Bloomberg G (2006) Omalizumab for asthma. N Engl J Med 354(2689):2695Google Scholar
  4. 4.
    Gandini S, Lowenfels AB, Jaffee EM, Armstrong TD, Maisonneuve P (2005) Allergies and the risk of pancreatic cancer: a meta-analysis with review of epidemiology and biological mechanisms. Cancer Epidemiol Biomarkers Prev 14:1908–1916PubMedGoogle Scholar
  5. 5.
    Linos E, Raine T, Alosno A, Michaud D (2007) Atopy and risk of brain tumors: a meta-analysis. J Natl Cancer Inst 99:1544–1550PubMedGoogle Scholar
  6. 6.
    Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM (2007) Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 370:59–67PubMedGoogle Scholar
  7. 7.
    Jensen-Jarolim E, Achatz G, Turner MC, Karagiannis S, Legrand F, Capron M, Penichet ML, Rodriguez JA, Siccardi AG, Vangelista L, Riemer AB, Gould H (2008) AllergoOncology: the role of IgE-mediated allergy in cancer. Allergy 63:1255–1266PubMedGoogle Scholar
  8. 8.
    Fu SL, Pierre J, Smith-Norowitz TA, Hagler M, Bowne W, Pincus MR, Mueller CM, Zenilman ME, Bluth MH (2008) Immunoglobulin E antibodies from pancreatic cancer patients mediate antibody-dependent cell-mediated cytotoxicity against pancreatic cancer cells. Clin Exp Immunol 153:401–409PubMedGoogle Scholar
  9. 9.
    Wang H, Diepgen T (2005) Is atopy a protective or a risk factor for cancer? A review of epidemiological studies. Allergy 60:1098–1111PubMedGoogle Scholar
  10. 10.
    Bellia V, Pedone C, Catalano F, Zito A, Davi E, Palange S, Forastiere F, Incalzi RA (2007) Asthma in the elderly. Mortality rate and associated risk factors for mortality. Chest 132:1175–1182PubMedGoogle Scholar
  11. 11.
    Brenner AV, Butler MA, Wang SS, Ruder AM, Rothman N, Schulte PA, Chanock SJ, Fine HA, Linet MS, Inskip PD (2007) Single-nucleotide polymorphisms in selected cytokine genes and risk of adult glioma. Carcinogenesis 28:2543–2547PubMedGoogle Scholar
  12. 12.
    Brown DB, Young KE, Anda RF, Giles WH (2005). Asthma and risk of death from lung cancer: NHANES II Mortality Study. J Asthma 42:597–600PubMedGoogle Scholar
  13. 13.
    Brown DB, Young KE, Anda RF, Felitti VJ, Giles WH (2006) Re: Asthma and the risk of lung cancer. Findings from the Adverse Childhood Experiences (ACE). Cancer Causes Control 17:349–350PubMedGoogle Scholar
  14. 14.
    Castaing M, Youngson J, Zaridze D, Szeszenia-Dabrowska N, Rudnai P, Lissowska J, Fabianova E, Mates D, Bencko V, Foretova L, Navratilova M, Janout V, Fletcher T, Brennan P, Boffetta P (2005) Is the risk of lung cancer reduced among eczema patients? Am J Epidemiol 162:542–547PubMedGoogle Scholar
  15. 15.
    Eppel A, Cotterchio M, Gallinger S (2007) Allergies are associated with reduced pancreas cancer risk: A population-based case-control study in Ontario, Canada. Int J Cancer 121:2241–2245PubMedGoogle Scholar
  16. 16.
    Eriksson N, Mikoczy Z, Hagmar L (2005) Cancer incidence in 13811 patients skin tested for allergy. J Invest Allergol Clin Immunol 15:161–166Google Scholar
  17. 17.
    Frostad A, Soyseth V, Haldorsen T, Andersen A, Gulsvik A (2008) Impact of respiratory symptoms on lung cancer: 30-year follow-up of an urban population. Lung Cancer 60:22–30PubMedGoogle Scholar
  18. 18.
    Gonzalez-Perez A, Fernandez-Vidaurre C, Rueda A, Rivero E, Garcia Rodriguez LA (2006) Cancer incidence in a general population of asthma patients. Pharmacoepidemiol Drug Saf 15:131–138PubMedGoogle Scholar
  19. 19.
    Gorlova OY, Zhang Y, Schabath MB, Lei L, Zhang Q, Amos CI, Spitz MR (2006) Never smokers and lung cancer risk: a case-control study of epidemiological factors. Int J Cancer 118:1798–1804PubMedGoogle Scholar
  20. 20.
    Hagstromer L, Ye W, Nyren O, Emtestam L (2005) Incidence of cancer among patients with atopic dermatitis. Arch Dermatol 141:1123–1127PubMedGoogle Scholar
  21. 21.
    Harding NJ, Birch JM, Hepworth SJ, McKinney PA, on behalf of the UKCCS investigators (2008) Atopic dysfunction and risk of central nervous system tumours in children. Eur J Cancer 44:92–99PubMedGoogle Scholar
  22. 22.
    Koh W-P, Yuan J-M, Wang R, Seow A, Lee H-P, Yu MC (2008) Chronic rhinosinusitis and risk of lung cancer in the Singapore Chinese Health Study. Int J Cancer 123:1398–1402PubMedGoogle Scholar
  23. 23.
    Lindelof B, Granath F, Tengvall-Linder M, Ekbom A (2005) Allergy and cancer. Allergy 60:1116–1120PubMedGoogle Scholar
  24. 24.
    Lo A-C, Soliman AS, El-Ghawalby N, Abdel-Wahab M, Fathy O, Khaled HM, Omar S, Hamilton SR, Greenson JK, Abbruzzese JL (2007) Lifestyle, occupational, and reproductive factors in relation to pancreatic cancer risk. Pancreas 35:120–129PubMedGoogle Scholar
  25. 25.
    Olesen AB, Engholm G, Storm HH, Thestrup-Pedersen K (2005) The risk of cancer among patients previously hospitalized for atopic dermatitis. J Invest Dermatol 125:445–449PubMedGoogle Scholar
  26. 26.
    Olson SH, Orlow I, Simon J, Tommasi D, Roy P, Bayuga S, Ludwig E, Zauber AG, Kurtz RC (2007) Allergies, variants in IL-4 and IL-4Rα genes, and risk of pancreatic cancer. Cancer Detect Prev 31:345–351PubMedGoogle Scholar
  27. 27.
    Pelucchi C, Naldi L, Di Landro A, La Vecchia C, on behalf of the Oncology Study Group of the Italian Group for Epidemiologic Research in Dermatology (GISED) (2008) Anthropometric measures, medical history and risk of basal cell carcinoma in an Italian case-control study. Dermatology 216:271–276PubMedGoogle Scholar
  28. 28.
    Petridou ET, Chavelas C, Dikalioti SK, Dessypris N, Terzidis A, Nikoulis DI, Markopoulos C, PapadiamantisY, Germenis AE (2007) Breast cancer risk in relation to most prevalent IgE specific antibodies: a case-control study in Greece. Anticancer Res 27:1709–1714PubMedGoogle Scholar
  29. 29.
    Prizment AE, Folsom AR, Cerhan JR, Flood A, Ross JA, Anderson KE (2007) History of allergy and reduced incidence of colorectal cancer, Iowa Women’s Health Study. Cancer Epidemiol Biomarkers Prev 16:2357–2362PubMedGoogle Scholar
  30. 30.
    Ramanakumar A, Parent M-E, Menzies D, Siemiatycki J (2006) Risk of lung cancer following nonmalignant respiratory conditions: Evidence from two case-control studies in Montreal, Canada. Lung Cancer 53:5–12PubMedGoogle Scholar
  31. 31.
    Schlehofer B, Schlaefer K, Blettner M, Berg G, Bohler E, Hettinger I, Kunna-Grass K, Wahrendorf J, Schuz J (2007) Environmental risk factors for sporadic acoustic neuroma (Interphone Study Group, Germany). Eur J Cancer 43:1741–1747PubMedGoogle Scholar
  32. 32.
    Schneider B, Pulhorn H, Rohrig B, Rainov NG (2005) Predisposing conditions and risk factors for development of symptomatic meningioma in adults. Cancer Detect Prev 29:440–447PubMedGoogle Scholar
  33. 33.
    Schoemaker MJ, Swerdlow AJ, Hepworth SJ, McKinney PA, van Tongeren M, Muir KR (2006) History of allergies and risk of glioma in adults. Int J Cancer 119:2165–2172PubMedGoogle Scholar
  34. 34.
    Schoemaker MJ, Swerdlow AJ, Auvinen A, Christensen HC, Feychting M, Johansen C, Klaeboe L, Lonn S, Salminen T, Tynes T (2006) Medical history, cigarette smoking and risk of acoustic neuroma: an international case-control study. Int J Cancer 120:103–110Google Scholar
  35. 35.
    Schoemaker MJ, Swerdlow AJ, Hepworth SJ, van Tongeren M, Muir KR, McKinney PA (2007) History of allergic disease and risk of meningioma. Am J Epidemiol 165:477–485PubMedGoogle Scholar
  36. 36.
    Schwartzbaum JA, Ahlbom A, Lonn S, Malmer B, Wigertz A, Auvinen A, Brookes AJ, Christensen HC, Henriksson R, Johansen C, Salminen T, Schoemaker MJ, Swerdlow AJ, Debinski W, Feychting M (2007) An international case-control study of interleukin-4Rα, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk. Cancer Epidemiol Biomarkers Prev 16:2448–2454PubMedGoogle Scholar
  37. 37.
    Seow A, Ng DPK, Choo S, Eng P, Poh W-T, Ming T, Wang Y-T (2006) Joint effect of asthma/atopy and an IL-6 gene polymorphism on lung cancer risk among lifetime non-smoking Chinese women. Carcinogenesis 27:1240–1244PubMedGoogle Scholar
  38. 38.
    Wang H, Rothenbacher D, Low M, Stegmaier C, Brenner H, Diepgen TL (2006) Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung and colorectum. Int J Cancer 119:695–701PubMedGoogle Scholar
  39. 39.
    Wiemels JL, Wiencke JK, Kelsey KT, Moghadassi M, Rice T, Urayama KY, Miike R, Wrensch M (2007) Allergy-related polymorphisms influence glioma status and serum IgE levels. Cancer Epidemiol Biomarkers Prev 16:1229–1235PubMedGoogle Scholar
  40. 40.
    Wigertz A, Lonn S, Schwartzbaum J, Hall P, Auvinen A, Christensen HC, Johansen C, Klaeboe L, Salminen T, Schoemaker MJ, Swerdlow AJ, Tynes T, Feychting M (2007) Allergic conditions and brain tumor risk. Am J Epidemiol 166:941–950PubMedGoogle Scholar
  41. 41.
    Wu X, Lin J, Etzel C, Dong Q, Gorlova OY, Zhang Q, Amos CI, Spitz MR (2007) Interplay between mutagen sensitivity and epidemiological factors in modulating lung cancer risk. Int J Cancer 120:2687–2695PubMedGoogle Scholar
  42. 42.
    Tennis P, Sherrill D, Fernandez C, Dolan C (2005) Cancer risk in asthmatic populations. Ann Allergy Asthma Immunol 95:354–360PubMedGoogle Scholar
  43. 43.
    Frentzel-Beyme R, Becher H, Salzer-Kuntschik M, Kotz R, Salzer M (2004) Factors affecting the incident juvenile bone tumors in an Austrian case-control study. Cancer Detect Prev 28:159–169PubMedGoogle Scholar
  44. 44.
    Lightfoot N, Conlon M, Kreiger N, Sass-Kartsak A, Purdham J, Darlington G (2004) Medical history, sexual, and maturational factors and prostate cancer risk. Ann Epidemiol 14:655–662PubMedGoogle Scholar
  45. 45.
    Menegaux F, Olshan AF, Neglia JP, Pollock BH, Bondy ML (2004) Day care, childhood infections, and risk of neuroblastoma. Am J Epidemiol 159:843–851PubMedGoogle Scholar
  46. 46.
    Milan T, Verkasalo PK, Kaprio J, Koskenvuo M (2003) Lifestyle differences in twin pairs discordant for basal cell carcinoma of the skin. Br J Dermatol 149:115–123PubMedGoogle Scholar
  47. 47.
    Ming ME, Levy R, Hoffstad O, Filip J, Abrams BB, Fernandez C, Margolis DJ (2004) The lack of a relationship between atopic dermatitis and nonmelanoma skin cancers. J Am Acad Dermatol 50:357–362PubMedGoogle Scholar
  48. 48.
    Schuz J, Kaletsch U, Meinert R, Kaatsch P, Spix C, Michaelis J (2001) Risk factors for neuroblastoma at different stages of disease. Results from a population-based case-control study in Germany. J Clin Epidemiol 54:702–709PubMedGoogle Scholar
  49. 49.
    Schwartzbaum J, Ahlbom A, Malmer B, Lonn S, Brookes AJ, Doss H, Debinshi W, Henriksson R, Feychting M (2005) Polymorphisms associated with asthma are inversely related to glioblastoma multiforme. Cancer Res 65:6459–6465PubMedGoogle Scholar
  50. 50.
    Kaaber K (1976) Occurrence of malignant neoplasms in patients with atopic dermatitis. Acta Derm Venereol 56:445–447Google Scholar
  51. 51.
    Allegra J, Lipton A, Harvey H, Luderer J, Brenner D, Mortel R, Demers L, Gillin M, White D, Trautlein J (1976) Decreased prevalence of immediate hypersensitivity (atopy) in a cancer population. Cancer Res 36:3225–3226PubMedGoogle Scholar
  52. 52.
    Augustin R, Chandradasa KD (1971) IgE levels and allergic skin reactions in cancer and non-cancer patients. Int Arch Allergy Immunol 41:141–143Google Scholar
  53. 53.
    Chilvers C, Johnson B, Leach S, Taylor C, Vigar E (1986) The common cold, allergy, and cancer. Br J Cancer 54:123–126PubMedGoogle Scholar
  54. 54.
    Cockroft DW, Klein GJ, Dovevan RE, Copland GM (1979) Is there a negative correlation between malignancy and respiratory atopy? Ann Allergy 43:345–347Google Scholar
  55. 55.
    Fisherman EW (1960) Does the allergic diathesis influence malignancy? J Allergy Clin Immunol 31:74–78Google Scholar
  56. 56.
    Henderson BE, Bogdanoff E, Gerkins VR, SooHoo J, Arthur M (1974) Evaluation of cancer risk in a retirement community. Cancer Res 34:1045–1048PubMedGoogle Scholar
  57. 57.
    Johnson KJ (1979) Cancer and allergy. Ann Allergy 43:375PubMedGoogle Scholar
  58. 58.
    Logan J, Saker D (1953) The incidence of allergic disorders in cancer. N Z Med J 52:210–212PubMedGoogle Scholar
  59. 59.
    Mackay WD (1966) The incidence of allergic disorders and cancer. Br J Cancer 20:434–437PubMedGoogle Scholar
  60. 60.
    McKee WD, Arnold CA, Perlman MD (1967) A double blind study of the comparative incidence of malignancy and allergy. J Allergy 39:294–301PubMedGoogle Scholar
  61. 61.
    Meers PD (1973) Allergy and cancer. Lancet 1:884–885PubMedGoogle Scholar
  62. 62.
    Moussa MAA, Karnik AM, Omar YT, Fenech FF (1985) On the analysis of three-dimensional contingency tables – application to the influence of allergy and age on cancer. Methods Inf Med 24:35–36PubMedGoogle Scholar
  63. 63.
    Petroianu A, Chaves DNB, De Oliveira O Jr (1995) Comparative incidence of allergy in the presence or absence of cancer. J Int Med Res 23:358–363PubMedGoogle Scholar
  64. 64.
    Shapiro S, Heinonen OP, Siskind V (1971) Cancer and allergy. Cancer 28:396PubMedGoogle Scholar
  65. 65.
    Vena JE, Bona JR, Byers TE, Middleton E Jr, Swanson MK, Graham S (1985) Allergy-related diseases and cancer: an inverse association. Am J Epidemiol 122:66–74PubMedGoogle Scholar
  66. 66.
    Kallen B, Gunnarskog J, Conradson T-B (1993) Cancer risk in asthmatic subjects selected from hospital discharge registry. Eur Respir J 6:694–697PubMedGoogle Scholar
  67. 67.
    Vesterinen E, Pukkala E, Timonon T, Aromaa A (1993) Cancer incidence among 78 000 asthmatic patients. Int J Epidemiol 22:976–982PubMedGoogle Scholar
  68. 68.
    Eriksson NE, Holmen A, Hogstedt B, Mikoczy Z, Hagmar L (1995) A prospective study of cancer incidence in a cohort examined for allergy. Allergy 50:718–722PubMedGoogle Scholar
  69. 69.
    Mills PK, Beeson WL, Fraser GE, Phillips RL (1992) Allergy and cancer: organ site-specific results from the Adventist Health Study. Am J Epidemiol 136:287–295PubMedGoogle Scholar
  70. 70.
    Turner M, Chen Y, Krewski D, Ghadirian P, Thun MJ, Calle EE (2005) Cancer mortality among US men and women with asthma and hay fever. Am J Epidemiol 162:212–221PubMedGoogle Scholar
  71. 71.
    Santillan A, Camargo C Jr, Colditz G (2003) A meta-analysis of asthma and risk of lung cancer (United States). Cancer Causes Control 14:327–334PubMedGoogle Scholar
  72. 72.
    Schabath MB, Delclos GL, Martynowicz MM, Greisinger AJ, Lu C, Wu X, Spitz MR (2005) Opposing effects of emphysema, hay fever, and select genetic variants on lung cancer risk. Am J Epidemiol 161:412–422PubMedGoogle Scholar
  73. 73.
    Talbot-Smith A, Fritschi L, Divitini ML, Mallon DFJ, Knuiman MW (2003) Allergy, atopy, and cancer: a prospective study of the 1981 Busselton Cohort. Am J Epidemiol 157:606–612PubMedGoogle Scholar
  74. 74.
    Vandentorren S, Baldi I, Annesi-Maesano I, Charpin D, Neukirch F, Filleul L, Cantagrel A, Tessier JF (2003) Long-term mortality among adults with or without asthma in the PAARC study. Eur Respir J 21:462–467PubMedGoogle Scholar
  75. 75.
    Wu AH, Yu MC, Thomas DC, Pike MC, Henderson BE (1988) Personal and family history of lung disease as risk factors for adenocarcinoma of the lung. Cancer Res 48:7279–7284PubMedGoogle Scholar
  76. 76.
    Alavanja MCR, Brownson RC, Boice JD Jr, Hock E (1992) Preexisting lung disease and lung cancer among nonsmoking women. Am J Epidemiol 136:623–632PubMedGoogle Scholar
  77. 77.
    Wu AH, Fontham ETH, Reynolds P, Greenberg RS, Buffler P, Liff J, Boyd P, Henderson BE (1995) Previous lung disease and risk of lung cancer among lifetime nonsmoking women in the United States. Am J Epidemiol 141:1023–1032PubMedGoogle Scholar
  78. 78.
    Osann KE, Lowery JT, Schell MJ (2000) Small cell lung cancer in women: risk associated with smoking, prior respiratory disease, and occupation. Lung Cancer 28:1–10PubMedGoogle Scholar
  79. 79.
    Boffetta P, Ye W, Boman G, Nyren O (2002) Lung cancer risk in a population-based cohort of patients hospitalized for asthma in Sweden. Eur Respir J 19:127–133PubMedGoogle Scholar
  80. 80.
    Littman AJ, Thornquist MD, White E, Jackson LA, Goodman GE, Vaughan TL (2004) Prior lung disease and risk of lung cancer in a large prospective study. Cancer Causes Control 15:819–827PubMedGoogle Scholar
  81. 81.
    Brenner AV, Wang Z, Kleinerman RA, Wang Longde, Zhang S, Metayer C, Chen K, Lei S, Cui H, Lubin, JH (2001) Previous pulmonary diseases and risk of lung cancer in Gansu Province, China. Int J Epidemiol 30:118–124Google Scholar
  82. 82.
    Hospers JJ, Postma DS, Rigcken B, Weiss ST, Schouten JP (2000) Histamine airway hyper-responsiveness and mortality from chronic obstructive pulmonary disease: a cohort study. Lancet 356:1313–1317PubMedGoogle Scholar
  83. 83.
    Wiemels JL, Wiencke JK, Patoka J, Moghadassi M, Chew T, McMillan A, Miike R, Barger G, Wrensch M (2004) Reduced immunoglobulin E and allergy among adults with glioma compared with controls. Cancer Res 64:8468–8473PubMedGoogle Scholar
  84. 84.
    Brenner AV, Linet MS, Fine HA, Shapiro WR, Selker RG, Black PM, Inskip PD (2002) History of allergies and autoimmune diseases and risk of brain tumors in adults. Int J Cancer 99:252–259PubMedGoogle Scholar
  85. 85.
    Giuffre R, Liccardo G, Pastore FS, Spallone A, Vagnozzi R (1990) Potential risk factors for brain tumors in children. Childs Nerv Syst 6:8–12PubMedGoogle Scholar
  86. 86.
    Bosetti C, Talamini R, Franceschi S, Negri E, Giacosa A, La Vecchia C (2004) Allergy and the risk of selected digestive and laryngeal neoplasms. Eur J Cancer Prev 13:173–176PubMedGoogle Scholar
  87. 87.
    Vobecky J, Caro J, Devroede G (1983) A case-control study of risk factors for large bowel carcinoma. Cancer 51:1958–1963PubMedGoogle Scholar
  88. 88.
    Ghadirian P, Maisonneuve P, Perret C, Lacroix A, Boyle P (1998) Epidemiology of sociodemographic characteristics, lifestyle, medical history, and colon cancer: a case-control study among French Canadians in Montreal. Cancer Detect Prev 22:396–404PubMedGoogle Scholar
  89. 89.
    Kune GA, Kune S, Watson LF (1988) Colorectal cancer risk, chronic illnesses, operations, and medications: case control results from the Melbourne Colorectal Cancer Study. Cancer Res 48:4399–4404PubMedGoogle Scholar
  90. 90.
    La Vecchia C, D’Avanzo B, Negri E, Franceschi S (1991) History of selected diseases and the risk of colorectal cancer. Eur J Cancer 27:582–586PubMedGoogle Scholar
  91. 91.
    Montgomery S, Ehlin A, Sparen P, Franceschi S (2002) Childhood indicators of susceptibility to subsequent cervical cancer. Br J Cancer 87:989–993PubMedGoogle Scholar
  92. 92.
    Ohrui T, Yamaya M, Sato T, Matsui T, Sasaki H, Namina T (2002) Risk of prostate cancer in older Japanese asthmatics. J Am Geriatr Soc 50:202PubMedGoogle Scholar
  93. 93.
    Swerdlow AJ, Huttly SRA, Smith PG (1987) Testicular cancer and antecedent diseases. Br J Cancer 55:97–103PubMedGoogle Scholar
  94. 94.
    McWhorter WP (1988) Allergy and risk of cancer. Cancer 62:451–455PubMedGoogle Scholar
  95. 95.
    Hedderson MM, Malone KE, Daling JR, White E (2003) Allergy and risk of breast cancer among young women (United States). Cancer Causes Control 14:619–626PubMedGoogle Scholar
  96. 96.
    Dai Q, Zheng W, Ji B-T, Shu X-O, Jin F, Cheng H-X, Gao Y-T (1997) Prior immunity-related medical conditions and oesophageal cancer risk: a population-based case-control study in Shanghai. Eur J Cancer Prev 6:152–157PubMedGoogle Scholar
  97. 97.
    Ye W, Chow W-H, Lagergren J, Boffetta P, Boman G, Adami H-O, Nyren O (2001) Risk of adenocarcinomas of the oesophagus and gastric cardia in patients hospitalized for asthma. Br J Cancer 85:1317–1321PubMedGoogle Scholar
  98. 98.
    Steineck G, Wiholm BE, Gerhardsson de Verder M (1995) Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. Acta Oncol 34:741–748PubMedGoogle Scholar
  99. 99.
    Kim W-J, Lee H-L, Lee S-C, Kim Y-T, Kim H (2000) Polymorphisms of n-acetyltransferase 2, glutathione s-transferase mu and theta genes as risk factors of bladder cancer in relation to asthma and tuberculosis. J Urol 164:209–213PubMedGoogle Scholar
  100. 100.
    Beral V, Evans S, Shaw H, Milton G (1983) Cutaneous factors related to the risk of malignant melanoma. Br J Dermatol 109:165–172PubMedGoogle Scholar
  101. 101.
    Margolis D, Bilker W, Hennessy S, Vittorio C, Santanna J, Strom BL (2001) The risk of malignancy associated with psoriasis. Arch Dermatol 137:778–783PubMedGoogle Scholar
  102. 102.
    Negri E, Ron E, Franceschi S, La Vecchia C, Preston-Martin S, Kolonel L, Kleinerman RA, Mabuchi K, Jin F, Wingren G, Hallquist A, Levi F, Linos A, Fraumeni JF Jr (2002) Risk factors for medullary thyroid carcinoma: a pooled analysis. Cancer Causes Control 13:365–372PubMedGoogle Scholar
  103. 103.
    Hallgren R, Arrendal H, Hiesche K, Lundquist G, Nou E, Zetterstrom O (1981) Elevated serum immunoglobulin E in bronchial carcinoma: its relation to the histology and prognosis of the cancer. J Allergy Clin Immunol 67:398–406PubMedGoogle Scholar
  104. 104.
    McDuffie HH, Cockroft DW, Talebi Z, Klaassen DJ, Dosman JA (1988) Lower prevalence of positive atopic skin tests in lung cancer patients. Chest 93:241–246PubMedGoogle Scholar
  105. 105.
    McDuffie HH (1991) Atopy and primary lung cancer. Chest 99:404–407PubMedGoogle Scholar
  106. 106.
    Michils A, Yernault J-C, Noel E, Gossart B, Servais G, Duchateau J (1992) Abnormal humoral immune response to mucosal antigenic stimulation in patients with lung cancer. Cancer 69:2252–2257PubMedGoogle Scholar
  107. 107.
    Sanchez-Borges M, De Orozco A, Arellano S, De Gallego V, Avila-Millian E, Suarez-Chacon R (1986) Preventive role of atopy in lung cancer. Clin Immunol Immunopathol 41:314–319PubMedGoogle Scholar
  108. 108.
    Van der Wal AM, Huizinga E, Orie NGM, Sluiter HJ, De Vries K (1966) Cancer and chronic non-specific lung disease (C.N.S.L.D.). Scand J Resp Dis 47:161–172Google Scholar
  109. 109.
    Tammemagi C, Neslund-Dudas C, Simoff M, Kvale P (2003) Impact of comorbidity on lung cancer survival. Int J Cancer 103:792–802PubMedGoogle Scholar
  110. 110.
    Vesterinen E, Karjalainen S, Timonen T, Pukkala E, Hakulinen T (1993) Survival rates in lung cancer patients with and without bronchial asthma. Acta Oncol 32:517–520PubMedGoogle Scholar
  111. 111.
    Yancik R, Wesley MN, Ries LAG, Havlik RJ, Long S, Edwards BK, Yates JW (1998) Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer 82:2123–2134PubMedGoogle Scholar
  112. 112.
    Yancik R, Wesley MN, Ries LAG, Havlik RJ, Edwards BK, Yates JW (2001) Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 and older. JAMA 285:885–892PubMedGoogle Scholar
  113. 113.
    Pompei R, Lampis G, Ingianni A, Nonnos D, Ionta MT, Massidda B (2004) Allergy and tumour outcome after primary cancer therapy. Int Arch Allergy Immunol 133:174–178PubMedGoogle Scholar
  114. 114.
    Wrensch M, Wiencke JK, Wiemels JL, Miike R, Patoka J, Moghadassi M, McMillan A, Kelsey KT, Aldape K, Lamborn KR, Parsa AT, Sison JD, Prados MD (2006) Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival. Cancer Res 66:4531–4541PubMedGoogle Scholar
  115. 115.
    Alderson M (1974) Mortality from malignant disease in patients with asthma. Lancet 2:1475–1477PubMedGoogle Scholar
  116. 116.
    Polednak AP (1975) Asthma and cancer mortality. Lancet 2:1147–1148PubMedGoogle Scholar
  117. 117.
    Robinette CD, Fraumeni JF Jr (1978) Asthma and subsequent mortality in world war II veterans. J Chron Dis 31:619–624PubMedGoogle Scholar
  118. 118.
    Hughes W, Raitz R (1979) A comparison of cancer occurrence in allergic and nonallergic populations. Ann Allergy 43:163–164PubMedGoogle Scholar
  119. 119.
    Markowe HLJ, Bulpitt CJ, Shipley MJ, Rose G, Crombie DL, Fleming DM (1987) Prognosis in adult asthma: a national study. BMJ 295:949–952PubMedGoogle Scholar
  120. 120.
    Reynolds P, Kaplan GA (1987) Asthma and cancer. Am J Epidemiol 125:539–540PubMedGoogle Scholar
  121. 121.
    Lange P, Ulrik CS, Vestbo J, for the Copenhagen City Health Study Group (1996) Mortality in adults with self-reported asthma. Lancet 347:1285–1289PubMedGoogle Scholar
  122. 122.
    Knuiman MW, James AL, Divitini ML, Ryan G, Bartholomew HC, Musk AW (1999) Lung function, respiratory symptoms, and mortality: results from the Busselton Health Study. Ann Epidemiol 9:297–306PubMedGoogle Scholar
  123. 123.
    Gergen PJ, Turkeltaub PC, Sempos CT (2000) Is allergen skin test reactivity a predictor of mortality? Findings from a national cohort. Clin Exp Allergy 30:1717–1723PubMedGoogle Scholar
  124. 124.
    Samet JM, Humble CG, Pathak DR (1986) Personal and family history of respiratory disease and lung cancer risk. Am Rev Respir Dis 134:466–470PubMedGoogle Scholar
  125. 125.
    Mayne ST, Buenconsejo J, Janerich DT (1999) Previous lung disease and risk of lung cancer among men and women nonsmokers. Am J Epidemiol 149:13–20PubMedGoogle Scholar
  126. 126.
    Mills PK, Beeson WL, Abbey DE, Fraser GE, Phillips RL (1988) Dietary habits and past medical history as related to fatal pancreas cancer risk among Adventists. Cancer 61:2578–2585PubMedGoogle Scholar
  127. 127.
    Stolzenberg-Solomon RZ, Pietinen P, Taylor PR, Virtamo J, Albanes D (2002) A prospective study of medical conditions, anthropometry, physical activity, and pancreatic cancer in male smokers (Finland). Cancer Causes Control 13:417–426PubMedGoogle Scholar
  128. 128.
    Lin RS, Kessler II (1981) A multifactorial model for pancreatic cancer in man: epidemiologic evidence. JAMA 245:147–152PubMedGoogle Scholar
  129. 129.
    Gold EB, Gordis L, Diener MD, Seltser R, Boitnott JK, Bynum TE, Hutcheon DF (1985) Diet and other risk factors for cancer of the pancreas. Cancer 55:460–467PubMedGoogle Scholar
  130. 130.
    Mack TM, Yu MC, Hanisch R, Henderson BE (1986) Pancreas cancer and smoking, beverage consumption, and past medical history. JCNI 76:49–60Google Scholar
  131. 131.
    Farrow DC, Davis S (1990) Risk of pancreatic cancer in relation to medical history and the use of tobacco, alcohol and coffee. Int J Cancer 45:816–820PubMedGoogle Scholar
  132. 132.
    La Vecchia C, Negri E, D’Avanzo B, Ferraroni M, Gramenzi A, Savoldelli R, Boyle P, Franceschi S (1990) Medical history, diet and pancreatic cancer. Oncology 47:463–466PubMedGoogle Scholar
  133. 133.
    Jain M, Howe GR, St. Louis P, Miller AB (1991) Coffee and alcohol as determinants of risk of pancreas cancer: a case-control study from Toronto. Int J Cancer 47:384–389PubMedGoogle Scholar
  134. 134.
    Bueno de Mesquita HB, Maisonneuve P, Moerman CJ, Walker AM (1992) Aspects of medical history and exocrine carcinoma of the pancreas: a population-based case-control study in the Netherlands. Int J Cancer 52:17–23Google Scholar
  135. 135.
    Kalapothaki V, Tzonou A, Hsieh C-C, Toupaadaki N, Karakatsani A, Trichopoulos D (1993) Tobacco, ethanol, coffee, pancreatitis, diabetes mellitus, and cholelithiasis as risk factors for pancreatic carcinoma. Cancer Causes Control 4:375–382PubMedGoogle Scholar
  136. 136.
    Dai Q, Zheng W, Ji B-T, Shu X-O, Jin F, Zhu J-L, Gao Y-T (1995) Prior immunity-related medical conditions and pancreatic cancer risk in Shanghai. Int J Cancer 63:337–340PubMedGoogle Scholar
  137. 137.
    Silverman DT, Schiffman M, Everhart J, Goldstein A, Lillemoe KD, Swanson GM, Schwartz AG, Brown LM, Greenberg RS, Schoenberg JB, Pottern LM, Hoover RN, Fraumeni JF Jr (1999) Diabetes mellitus, other medical conditions and familial history of cancer as risk factors for pancreatic cancer. Br J Cancer 80:1830–1837PubMedGoogle Scholar
  138. 138.
    Holly EA, Eberle CA, Bracci PM (2003) Prior history of allergies and pancreatic cancer in the San Francisco Bay Area. Am J Epidemiol 158:432–441PubMedGoogle Scholar
  139. 139.
    Schwartzbaum J, Jonsson F, Ahlbom A, Preston-Martin S, Lonn S, Soderberg KC, Feychting M (2003) Cohort studies of association between self-reported allergic conditions, immune-related diagnoses and glioma and meningioma risk. Int J Cancer 106:423–428PubMedGoogle Scholar
  140. 140.
    Hochberg F, Toniolo P, Cole P (1990) Nonoccupational risk indicators of glioblastoma in adults. J Neurooncol 8:55–60PubMedGoogle Scholar
  141. 141.
    Schlehofer B, Blettner M, Preston-Martin S, Niehoff D, Wahrendorf J, Arslan A, Alhbom A, Choi WN, Giles GG, Howe GR, Little J, Menegoz F, Ryan P (1999) Role of medical history in brain tumor development. Results from the International Adult Brain Tumor Study. Int J Cancer 82:155–160PubMedGoogle Scholar
  142. 142.
    Wiemels JL, Wiencke JK, Sison JD, Miike R, McMillan A, Wrensch M (2002) History of allergies among adults with glioma and controls. Int J Cancer 98:609–615PubMedGoogle Scholar
  143. 143.
    Ryan P, Lee MW, North B, McMichael AJ (1992) Risk factors for tumors of the brain and meninges: results from the Adelaide Adult Brain Tumor Study. Int J Cancer 51:20–27PubMedGoogle Scholar
  144. 144.
    Schlehofer B, Blettner M, Becker N, Martinsohn C, Wahrendorf J (1992) Medical risk factors and the development of brain tumors. Cancer 69:2541–2547PubMedGoogle Scholar
  145. 145.
    Cicuttini FM, Hurley SF, Forbes A, Donnan GA, Salzberg M, Giles GG, McNeil JJ (1997) Association of adult glioma with medical conditions, family and reproductive history. Int J Cancer 71:203–207PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, Faculty of Graduate and Post-Graduate StudiesUniversity of OttawaOttawaCanada

Personalised recommendations