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Preservatives

  • Sara FloresEmail author
  • Howard Maibach
Chapter

Abstract

Preservatives are common ingredients indicated in allergic contact dermatitis (ACD). Health care practitioners should familiarize themselves with those most frequently used in cosmetics, drugs, and occupational exposure so that they can provide adequate care and education to affected patients. This chapter summarizes the preservatives used in the Standard Series Patch Test, which are also common causes of ACD. We also provide two case examples of ACD resulting from contact with the above additives.

Keywords

Preservatives Quaternium-15 Parabens Formaldehyde Allergic contact dermatitis Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) Methyldibromoglutaronitrile (MDBNG)/phenoxyethanol 

References

  1. 1.
    Lachapelle JM, Maibach HI. The Standard Series of Patch Tests. In: Patch Testing and Prick Testing: A Practical Guide/Official Publication of the ICDRG. Verlag, Berlin, Heidelberg: Springer; 2009: Chapter 4.Google Scholar
  2. 2.
    Lundov MD, Moesby L, Zachariae C, Johansen JD. Contamination versus preservation of cosmetics: a review on legislation, usage, infections, and contact allergy. Contact Dermatitis. 2009; 60: 70–78.PubMedCrossRefGoogle Scholar
  3. 3.
    Mirshahpanah P, Maibach H. Relationship of patch test positivity in a general versus an eczema population. Contact Dermatitis. 2007; 56: 125–130.PubMedCrossRefGoogle Scholar
  4. 4.
    Thyssen JP, Linneberg A, Menné T, Johansen JD. The epidemiology of contact allergy in the general population-prevalence and main findings. Contact Dermatitis. 2007; 57: 287–299.PubMedCrossRefGoogle Scholar
  5. 5.
    Marks JG, DeLeo VA. Contact and Occupational Dermatology. St. Louis (MI): Mosby Year Book; 1992.Google Scholar
  6. 6.
    Rietschel RL, Fowler JF. Fischer’s Contact Dermatitis. Hamilton (Ontario): BC Decker, Inc; 2008.Google Scholar
  7. 7.
    Zug KA, Warshaw EM, Fowler JF Jr., et al. Patch-test results of the North American Contact Dermatitis Group 2005–2006. Dermatitis. 2009; 20: 149–160.PubMedGoogle Scholar
  8. 8.
    Hauksson I, Pontén A, Gruvberger B, Isaksson M, Bruze M. Patch testing with formaldehyde 2.0% (0.60 mg/cm2) detects substantially more contact allergy to formaldehyde than 1.0%. Contact Dermatitis. In press.Google Scholar
  9. 9.
    Sasseville D. Hypersensitivity to preservatives. Dermatologic Therapy. 2004; 17: 251–263.PubMedCrossRefGoogle Scholar
  10. 10.
    Ortiz KJ, Yiannias JA. Contact dermatitis to cosmetics, fragrances, and botanicals. Dermatologic Therapy. 2004; 17: 264–271.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Dermatology, School of MedicineUniversity of California, San FranciscoSan FranciscoUSA

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