• Elena SchiopuEmail author
  • James R. Seibold


Scleroderma is a descriptive construct that defines a large family of ­diseases characterized clinically by thickening of the skin. Systemic sclerosis (SSc) is a complex disease affecting multiple organ systems and is the most ­representative and prevalent of this spectrum of disorders. Generalized subcutaneous morphea (GSM, morphea profunda) is a form of localized scleroderma that tends to spare the internal organs. We are presenting two cases illustrating the aforementioned clinical entities.


Scleroderma Fibrosing disorders Morphea 


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Division of RheumatologyUniversity of MichiganAnn ArborUSA

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