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Cutaneous Mastocytosis

  • Jason R. Catanzaro
  • Haig TcheurekdjianEmail author
Chapter

Abstract

Mastocytosis is a group of disorders characterized by an abnormal accumulation of mast cells in one or more organ systems. Cutaneous mastocytosis, by definition, is the restriction of mast cells to the skin although patients with this disease may have both cutaneous and systemic symptoms. Recognition of ­cutaneous mastocytosis is important, especially in children, as its prognosis is favorable in the majority of cases, and, while there is no cure, treatment options are available for symptomatic relief. Annual visits to monitor for signs of progression to systemic disease as well as patient education about potential triggers and consequences of mast cell degranulation are an important component of management.

Keywords

Cutaneous mastocytosis Urticaria pigmentosa Mastocytoma Tryptase Telangiectasia macularis eruptiva perstans Darier’s sign 

Notes

Acknowledgments

We gratefully thank Kord Honda, MD, Assistant Professor of Dermatology and Director of Dermatopathology at Case Western Reserve University, for providing the images of mastocytosis histology.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Allergy/Immunology Associates, IncClevelandUSA
  2. 2.Department of Medicine and PediatricsCase Western Reserve UniversityClevelandUSA

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