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Renin Angiotensin System and Cardiovascular Disease pp 1–5Cite as

Systemic Versus Local Renin Angiotensin Systems. An Overview

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Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

The concept of local renin angiotensin systems in the cardiovascular system is discussed, and evidence is presented that these systems work independently of the systemic one.

Particular attention was given to the presence of an intracrine renin angiotensin aldosterone system in the heart and the novel role of the mineralocorticoid receptor. Furthermore, the influence of the renin angiotensin system on cell volume regulation is briefly discussed.

This chapter includes an overview of these important biological concepts and provides an introduction to the topics that are discussed in detail by different authors throughout the book.

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Author information

Authors and Affiliations

  1. School of Medicine, Medical Sciences Campus, UPR, San Juan, PR, USA

    Walmor C. DeMello MD, PhD

  2. Ochnser Clinic Foundation, New Orleans, LA, USA

    Richard N. Re MD

Authors
  1. Walmor C. DeMello MD, PhD
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  2. Richard N. Re MD
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, University of Puerto Rico, San Juan, 00936, U.S.A.

    Walmor C. DeMello

  2. Ochsner Clinic Foundation, Jefferson Highway 1514 , New Orleans, 70121, U.S.A.

    Edward D. Frohlich

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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DeMello, W.C., Re, R.N. (2009). Systemic Versus Local Renin Angiotensin Systems. An Overview. In: DeMello, W., Frohlich, E. (eds) Renin Angiotensin System and Cardiovascular Disease. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-60761-186-8_1

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  • DOI: https://doi.org/10.1007/978-1-60761-186-8_1

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60761-185-1

  • Online ISBN: 978-1-60761-186-8

  • eBook Packages: MedicineMedicine (R0)

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