In summary, our knowledge of EGIDs is rapidly evolving; however, there is still much to be learned about the pathogenesis and treatment of these disorders. At the present time, it appears that eosinophilic enteritis is a chronic disorder characterized by the presence of diarrhea, abdominal pain, weight loss, and bloating. The clinical course appears to be characterized as being relapsing and remitting in nature. Successful treatment with prednisone or an elemental diet has been documented and other therapeutic interventions have been attempted with variable results. The underlying etiology for eosinophilic enteritis is unknown. The available evidence suggests a Th2-mediated process potentially driven by food antigens. The authors hope that they have provided a fundamental knowledge base from which the reader may be able to diagnose and treat EGIDs and hope that the readers join in the effort to further understand this fascinating group of disorders.
Key WordsEnteritis Eosinophil-associated gastrointestinal disorders (EGIDs) Eosinophils Esophagitis Food allergy
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