Antiviral Activity of Phytochemicals: A Current Perspective

  • Rajesh Naithani
  • Rajendra G. Mehta
  • Deepak Shukla
  • Susantha N. Chandersekera
  • Robert M. Moriarty
Chapter
Part of the Nutrition and Health book series (NH)

Key Points

A wide variety of active phytochemicals have been found to have therapeutic ­applications against genetically and functionally diverse viruses. The antiviral mechanism of these agents may be explained on the basis of their ­antioxidant activities, scavenging capacities, the inhibition of DNA, RNA synthesis, or the blocking of viral reproduction, etc. Numerous epidemiological and experimental studies have revealed that a large number of phytochemicals have promising antiviral activities. Especially in the last decade, a number of promising leads have been identified by a combination of in vitro and in vivo studies using diverse biological assays.

Key Words

Antiviral phytochemical infection replication flavonoids clinical ­trials mechanism 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Rajesh Naithani
    • 1
  • Rajendra G. Mehta
    • 2
    • 3
  • Deepak Shukla
    • 4
    • 5
  • Susantha N. Chandersekera
    • 6
  • Robert M. Moriarty
    • 2
    • 7
  1. 1.Drug Discovery DivisionIIT Resrach instituteChicagoUSA
  2. 2.Drug Discovery DivisionIIT Research InstituteChicagoUSA
  3. 3.Carcinogenesis Chemoprevention DivisionIIT Research InstituteChicagoUSA
  4. 4.Department of Microbiology and ImmunologyUniversity of IllinoisChicagoUSA
  5. 5.Department of Ophthalmology and Visual SciencesUniversity of IllinoisChicagoUSA
  6. 6.Department of ChemistryUniversity of Illinois at ChicagoChicagoUSA
  7. 7.Department of ChemistryUniversity of IllinoisChicagoUSA

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