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Hypertension and Stroke pp 211–224Cite as

Cerebral Small Vessel Disease, Hypertension, and Cognitive Function

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Part of the book series: Clinical Hypertension and Vascular Diseases ((CHVD))

Abstract

Vascular cognitive impairment (VCI) is a heterogeneous condition arising from a variety of neurovascular pathology, including large vessel ischemic infarction, hemorrhage, and the combination of cerebrovascular and Alzheimer’s pathology (1). However, VCI is primarily associated with subcortical gray and white matter pathology arising from small vessel disease. Hypertension is a major factor in the development of small vessel disease. In this chapter, we will focus on linkages between hypertension, small vessel disease, cognitive decline, and dementia.

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Authors and Affiliations

  1. Department of Neurology, University of Illinois at Chicago, Chicago, IL, USA

    Elizabeth K. Geary PhD

  2. Department of Neurology and Rehabilitation Medicine, Chicago Medical Center, University of Illinois, Chicago, IL, USA

    David L. Nyenhuis PhD

Authors
  1. Elizabeth K. Geary PhD
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  2. David L. Nyenhuis PhD
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Correspondence to Elizabeth K. Geary PhD .

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Editors and Affiliations

  1. College of Medicine, Dept. Neurology, University of Illinois, 912 S. Wood Street Room 855 N, Chicago, 60612, Illinois, USA

    Venkatesh Aiyagari

  2. University of Illinois, Department of Neurology and Rehabilitati, College of Medicine at Chicago, S. Wood St 912, Chicago, 60612, Illinois, USA

    Philip B. Gorelick

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Geary, E.K., Nyenhuis, D.L. (2011). Cerebral Small Vessel Disease, Hypertension, and Cognitive Function. In: Aiyagari, V., Gorelick, P. (eds) Hypertension and Stroke. Clinical Hypertension and Vascular Diseases. Humana Press. https://doi.org/10.1007/978-1-60761-010-6_13

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  • DOI: https://doi.org/10.1007/978-1-60761-010-6_13

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