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Childhood Obesity, Atherogenesis, and Adult Cardiovascular Disease

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Pediatric Obesity

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Natural history of atherosclerosis – Atherosclerosis was described as a medical curiosity in human arteries by numerous observers over the last three centuries. Early in the twentieth century, atherosclerosis of the coronary arteries was linked to thrombosis, arterial occlusion, and myocardial infarction (1) and is now known to be the arterial lesion underlying most forms of adult cardiovascular disease [coronary heart disease (CHD), stroke, abdominal aortic aneurysm, peripheral arterial disease]. The frequency of cardiovascular disease due to atherosclerosis increased in the United States and in the other industrialized countries until it became the leading cause of disability and death by the 1950s (2).

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Authors and Affiliations

  1. Southwest Foundation for Biomedical Research, San Antonio, TX, 78245-0549, USA

    Henry C. McGill Jr

  2. University of Texas Health Science Center, San Antonio, TX, 78229-3900, USA

    C. Alex McMahan

  3. Nemours Cardiac Center, Alfred I DuPont Hospital for Children, Wilmington, DE, 19803, USA

    Samuel S. Gidding

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  1. Henry C. McGill Jr
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  2. C. Alex McMahan
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  3. Samuel S. Gidding
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Editors and Affiliations

  1. Department of Pediatric Endocrinology, and Diabetes, Duke University, DUMC 3080, Durham, 27710, North Carolina, USA

    Michael Freemark

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McGill, H.C., McMahan, C.A., Gidding, S.S. (2010). Childhood Obesity, Atherogenesis, and Adult Cardiovascular Disease. In: Freemark, M. (eds) Pediatric Obesity. Contemporary Endocrinology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-60327-874-4_19

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  • DOI: https://doi.org/10.1007/978-1-60327-874-4_19

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