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Pediatric Obesity pp 253–263Cite as

The Long-Term Metabolic Complications of Childhood Obesity

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Part of the book series: Contemporary Endocrinology ((COE))

Abstract

Childhood obesity and associated insulin resistance (IR) and hyperinsulinemia (1–6) have broad-ranging metabolic effects that have profound impacts on adult health. They are associated with cardiovascular risk factors, including hypertension, hypertriglyceridemia, low HDL levels, and high cholesterol (HDL-C) levels, which track with time and are central to the long-term development of impaired fasting glucose (IFG), type 2 diabetes mellitus (T2DM), and the metabolic syndrome (2, 7, 8) (Fig. 1).

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Notes

  1. 1.

    This research was supported in part by American Heart Association (National)-9750129 N, NIH- HL62394, HC55025 and HL48941 (Dr Morrison) and by the Lipoprotein Research Fund of the Jewish Hospital of Cincinnati (Dr Glueck)

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Authors and Affiliations

  1. Cholesterol Center, Jewish Hospital of Cincinnati, Cincinnati, OH, 45229, USA

    Charles J. Glueck, Muhammad Umar, Naila Goldenberg & Ping Wang

  2. Division of Cardiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 45229, USA

    John A. Morrison

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  1. Charles J. Glueck
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  2. John A. Morrison
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  3. Muhammad Umar
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  4. Naila Goldenberg
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  5. Ping Wang
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  1. Department of Pediatric Endocrinology, and Diabetes, Duke University, DUMC 3080, Durham, 27710, North Carolina, USA

    Michael Freemark

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Glueck, C.J., Morrison, J.A., Umar, M., Goldenberg, N., Wang, P. (2010). The Long-Term Metabolic Complications of Childhood Obesity. In: Freemark, M. (eds) Pediatric Obesity. Contemporary Endocrinology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-60327-874-4_18

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  • DOI: https://doi.org/10.1007/978-1-60327-874-4_18

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