The term neuroimmunology means different things to different biomedical scientists and clinicians. This evolving and broad discipline includes the study of secreted immune cell products known as cytokines, lymphokines, monokines, and chemokines and their presence and actions in the central and peripheral nervous systems. Another area of study is that in which the nerve supply and nervous system regulation of lymphoid organs such as the spleen and thymus gland are considered. A third connotation of this word involves the investigation of how neuroendocrine substances of the hypothalamic-pituitary unit regulate the proliferation and activities of monocytes, macrophages, lymphocytes, and glial cells(considered by some to be the “macrophages of the brain”). A fourth implication of neuroimmunology is recognition of the fact that immune cells can produce neuroendocrine peptides such as adrenocorticotropic hormone (ACTH) and luteinizing hormone releasing hormone (LHRH). A fifth...
KeywordsThyroid Stimulate Hormone Vasoactive Intestinal Peptide Corticotropin Release Factor Thymus Gland Acquire Immune Deficiency Syndrome Patient
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