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Clinical Correlation

Disorders of Sleep
  • Gregory Cooper
  • Gerald Eichhorn

Although the exact role of sleep in humans and other animals has not been clearly determined, disruption of sleep can have serious consequences for the health of the affected individual. Disorders of sleep can result from a number of conditions, all with varied causes and associated symptoms. For example, one of the most common conditions resulting in disturbed sleep is obstructive sleep apnea syndrome. In this condition, patients experience either a relative collapse of the airway resulting in reduced airflow (hypopnea) or complete airway closure with resultant apnea. These episodes may occur hundreds of times per night with associated brief arousals and severely disrupted sleep continuity. The patient experiences significant and excessive daytime somnolence and may fall asleep frequently during the day, including while driving.

Disorders of Sleep May Be Related to Sleep Stage

Other disorders result from disturbances during specific stages of sleep. Sleep is normally separated into...

Keywords

Obstructive Sleep Apnea Obstructive Sleep Apnea Syndrome Excessive Daytime Somnolence Sleep Paralysis Muscle Atonia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Selected Readings

  1. Black JE, Brooks SN, Nishino S. Narcolepsy and syndromes of primary excessive daytime somnolence. Semin Neurol. 2004;24(3):271–282.PubMedCrossRefGoogle Scholar
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  4. Van den Pol, AN. Narcolepsy: a neurodegenerative disease of the hypocretin system? Neuron 2000;27:415–418.PubMedCrossRefGoogle Scholar

Copyright information

© Humana Press, Totowa, NJ 2008

Authors and Affiliations

  • Gregory Cooper
    • 1
  • Gerald Eichhorn
    • 2
  1. 1.Sanders-Brown Center on AgingThe University of Kentucky, The Lexington ClinicLexingtonUSA
  2. 2.The Lexington ClinicLexingtonUSA

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