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The Cerebellum

  • Charles R. Goodlett

Overview

The cerebellum, aptly named from Latin meaning “little brain,” accounts for only about 10% of the total weight of the brain (about 150 g in the adult human male) but contains more than 50% of the brain's neurons. The cerebellum is present in some form in all vertebrates. Its neurons and connectional anatomy are highly organized with a geometric regularity that repeats in a modular fashion over the entire cerebellum. Three major functional subdivisions can be identified in the mammalian cerebellum, corresponding with different phylogenetic origins: the vestibulocerebellum (archicerebellum), spinocerebellum (paleocerebellum), and cerebrocerebellum (neocerebellum). The cellular architecture of these divisions is remarkably uniform, but they differ in the source of their afferent input (vestibular, spinal, and corticopontine projections, respectively) and the targets of their efferent regulation. Because there are no associational/commissural connections between different regions...

Keywords

Purkinje Cell Granule Cell Cerebellar Cortex Vestibular Nucleus Mossy Fiber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This work represents a revision and extension of the chapter that appeared in the 2nd edition of Neuroscience in Medicine, authored by James R. West and John B. Geldard. Substantial portions of the text and most of the figures of their previous chapter were retained, some with modification. The author assumes full responsibility for the current version of this chapter.

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Copyright information

© Humana Press, Totowa, NJ 2008

Authors and Affiliations

  • Charles R. Goodlett
    • 1
  1. 1.Department of Psychology and Program in Medical NeuroscienceIndiana University-Purdue University IndianapolisIndianapolisUSA

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