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Clinical Correlation

Stroke
  • Gregory Cooper
  • Gerald Eichhorn
  • Robert Rodnitzky

Stroke is the third leading cause of death in the United States, with approximately 700,000 new or recurrent cases each year. The prevalence within the United States has been estimated at 4.7 million, with a cost of $51.2 billion annually. Stroke refers to the neurologic dysfunction resulting from a derangement of the blood supply to the brain or spinal cord. The neurologic symptoms of a stroke are often of sudden onset and may be temporary or permanent. Strokes may be ischemic, resulting from impaired blood flow, or hemorrhagic. Cerebral ischemia is a potentially reversible alteration of brain function that results from inadequate delivery of critical blood-borne substrates such as oxygen and glucose. Cerebral infarction occurs if ischemia is severe enough to kill cells. In this circumstance, there is a high likelihood of permanent dysfunction. The brain is particularly sensitive to severe ischemia, with irreversible cell death resulting in 2 to 3 minutes in some species and in...

Keywords

Middle Cerebral Artery Transient Ischemic Attack Basilar Artery Anterior Cerebral Artery Posterior Cerebral Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Selected Readings

  1. Barrett KM and Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurol Clin 2006;24:681–695.PubMedCrossRefGoogle Scholar
  2. Biller J. Vascular syndromes of the forebrain, brainstem, and cerebellum. In: Brazis P, Masdeu J, Biller J (eds.). Localization in clinical neurology, 4th edition. Boston: Little, Brown, 2001:523–557.Google Scholar
  3. Manno EM, Atkinson JL, Fulgham J, and Wijdicks EF. Emerging medical and surgical management strategies in the evaluation and treatment of intracerebral hemorrhage. Mayo Clin Proc 2005;80(3):420–433.PubMedCrossRefGoogle Scholar

Copyright information

© Humana Press, Totowa, NJ 2008

Authors and Affiliations

  • Gregory Cooper
    • 1
    • 2
  • Gerald Eichhorn
    • 3
  • Robert Rodnitzky
    • 4
  1. 1.Sanders-Brown Center on AgingThe University of KentuckyLexingtonUSA
  2. 2.Baptist Neurology CenterLexingtonUSA
  3. 3.The Lexington ClinicLexingtonUSA
  4. 4.Department Head of NeurologyUniversity of Iowa Hospitals and ClinicsIowa CityUSA

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