Abstract
In the setting of human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS), two well-characterized syndromes can present with fevers, rash, headache, and other nonspecific complaints that may mimic an allergic or immune system-mediated reaction. Both the HIV specialist and non-HIV health care provider need to recognize these syndromes to initiate effective treatment and prevent further complications. Here we present a case of acute HIV syndrome with a severe oral ulcer. Our second case highlights an individual presenting with abacavir hypersensitivity reaction in an otherwise healthy HIV patient.
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References
Veraldi, S., Lunardon, L., Persico, M.C., Francia, C., & Bottini, S., Multiple aphthoid syphilitic chancres of the oral cavity. Int J STD AIDS 19(7), 486–487 (2008).
Kelley, C.F., Barbour, J.D., & Hecht, F.M., The relation between symptoms, viral load, and viral load set point in primary HIV infection. J Acquir Immune Defic Syndr 45(4), 445–448 (2007).
Branson, B.M. et al., Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep 55 (RR-14), 1–17; quiz CE11–14 (2006).
Sidat, M.M. et al., Incidence of putative HIV superinfection and sexual practices among HIV-infected men who have sex with men. Sex Health 5(1), 61–67 (2008).
Hughes, C.A. et al., Abacavir hypersensitivity reaction: an update. Ann Pharmacother 42(3), 387–396 (2008).
Mallal, S. et al., HLA-B*5701 screening for hypersensitivity to abacavir. N Engl J Med 358(6), 568–579 (2008).
HHS, Guidelines for the use of antiretroviral agents in HIV-1 infected adults and adolescents. Department of Health and Human Services (January, 29), 1–128; Available at http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf(2008).
Phillips, E.J., Genetic screening to prevent abacavir hypersensitivity reaction: are we there yet? Clin Infect Dis 43(1), 103–105 (2006).
Martin, A.M. et al., Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc Natl Acad Sci USA 101(12), 4180–4185 (2004).
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© 2009 Humana Press, a part of Springer Science+Business Media, LLC
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Lim, D., Jensen, P. (2009). HIV/AIDS and Complications. In: Mahmoudi, M. (eds) Challenging Cases in Allergy and Immunology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-443-2_16
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DOI: https://doi.org/10.1007/978-1-60327-443-2_16
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