Insulin Use

  • Ronald A. Codario
Part of the Current Clinical Practice book series (CCP)


Several clinical trials covering thousands of patient cohorts have clearly demonstrated the correlation between the long-term macro and microvascular complications of diabetes and poorly controlled blood glucose with the subsequent benefits of tighter glycemic control. This data has made us all much more aware that insulin, used even in the early stages of diabetes, to insure proper control, can be invaluable in reducing mortality and morbidity. In fact, earlier insulin use reduces glucose toxicity, allows endogenous insulin to function more efficiently and reduces the strain on the deteriorating beta cell [1].

Key Words

Insulin therapy Human insulin preparations Insulin analogs Intermediate-acting insulins Pre-mixed insulins Biphasic insulins Multiple daily injections (MDI) Infusion pumps General therapeutic principles 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Ronald A. Codario
    • 1
  1. 1.University of Pennsylvania Health System Thomas Jefferson University HospitalPhiladelphiaUSA

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